SPAG8 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1506 Sequence: atggagacca acgggtctac ggagggatcg cggtcgcggt cgcgatcttt agacatacag cccagctccg aaggactggg gcccacttcg gaaccgtttc cttcttcaga tgacagtccc aggtcggccc tggcagctgc aaccgcagca gctgcagcgg ctgcatcagc tgctgcagct actgcagcct tcaccactgc caaagcagct gcattatcta caaagacccc agcgccctgt tctgagttca tggagccgtc ctctgacccc agccttcttg gggagccctg tgcgggaccc ggctttaccc acaatatagc ccatgggagt cttggctttg agcccgtcta tgtttcctgt attgctcagg acacttgcac tacaactgac catagttcta atcctggccc tgttccaggc tctagctctg ggcctgttct tggttccagc tcaggtgctg gccatggctc tggctctggc tctggtcctg gctgtggctc tgtccctggc tctggctctg gtcctggtcc tggctctggt cctggctctg gtcctggtca tggctctggc tctcatcctg gtcctgcctc tgggcctggt ccagacactg gccctgactc tgagctcagc ccctgtattc ctccagggtt cagaaacctg gtggcagatc gggtccttaa ctatacctcc tggagtcagc actgcccctg ggagccccag aaacaaccac cttgggaatt tttgcaagtc ttagaaccgg gtgcccgagg attatggaaa cccccagaca ttaaagggaa gcttatggtt tgctatgaaa ctttgccgcg gggccagtgc ctcctctaca actgggagga agagagagcc accaaccacc tggatcaagt cccaagcatg caggatggct ctgagagttt tttcttccga cacggacacc ggggactgct gactatgcaa ctaaagtcac ccatgccctc cagcaccacc cagaaagact cgtaccagcc accaggaaac gtctattggc cacttcgagg gaagcgtgaa gccatgctgg agatgctcct gcagcatcag atctgtaaag aggtgcaggc agaacaggaa cccacaagga agctcttcga ggttgagtct gtgacacacc atgactaccg aatggagctg gcacaagcag ggactcctgc cccaacaaag cctcacgact accgccagga gcaacctgag accttctgga tacagagggc accacagctg ccgacatggt ggccattgcc cacccaggta ccagcagcag aagactatct gacttggaaa gaatgggggt ttacaggagt ccaggaggtc ctttccgctc tcctaagagc cacacctggt gaatactcag taaacatttg cggaatgaat gaacaccctg tctgcagcag gacatggaca aataggctct gccatcagga aatgggaagc aagaaaacgg taactcaaga ggacagaggc Protein function: Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5- regulated transcriptional activation of CREM isoform tau. Involved in the acrosome reaction and in binding of sperm to the zona pellucida. Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis (PubMed:19548270). May play a role in fertility and microtubule formation through interaction with RANBP9 (PubMed:10500252). [The UniProt Consortium]