SOCS6 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1608 Sequence: atgaagaaaa ttagtcttaa aaccttacgg aaatctttta acttgaataa aagtaaagaa gaaactgatt tcatggtagt acaacaacca tcgctagcca gtgactttgg aaaagatgat tccttatttg gtagctgcta tggtaaagat atggccagct gcgatatcaa cggtgaagat gaaaaaggcg gaaaaaacag atcaaaaagc gagagcctga tgggtacgct aaaaaggcgg ctttctgcaa aacagaagtc aaaaggcaag gcgggcacac cctctgggag ctctgccgac gaggacacct tctcctcctc ctcagcaccc atagtcttta aagacgtgag agctcagagg ccgataaggt ccacgtcgct ccgcagccat cactacagtc ccgcgccgtg gcctctgcgg cccacaaact ccgaggagac ctgcatcaag atggaggtga gagtcaaggc cttggttcac tcttccagcc cgagtccagc cctgaatggc gtccggaagg atttccacga cctccagtct gagaccacgt gccaggagca agccaattca ctgaagagct cggcttctca taatggagac ctgcatcttc acctggatga acatgtgcct gtcgttattg gacttatgcc tcaggactac attcagtata ctgtgccttt agatgagggg atgtatcctt tggaaggatc acggagctat tgtctggaca gctcttctcc catggaagtc tctgcggttc ctcctcaagt gggagggcgc gctttccccg aggatgagag tcaggtagac caggacctag ttgtcgcccc agagatcttc gtggatcagt ccgtgaatgg cttgttgatt ggcaccacgg gagtcatgtt gcagagcccg agagcgggtc acgatgatgt ccctccactc tcaccattgc tacctccaat gcagaataat caaatccaaa ggaacttcag tggactcact ggcacagaag cccacgtggc tgaaagtatg cgctgtcatt tgaattttga tccgaactct gctcctgggg ttgcaagagt ttatgactca gtgcaaagta gtggtcccat ggttgtgaca agccttacag aggagctgaa aaaacttgca aagcaaggat ggtactgggg accaatcaca cgttgggagg cagaagggaa gctagcaaac gtgccagatg gttcttttct tgttcgggac agttctgacg accgttacct tttaagcttg agctttcgct cccatggtaa aacacttcac actagaattg agcactcaaa tggtaggttt agcttttatg aacagccaga tgtggaagga catacgtcca tagttgatct aattgagcat tcaatcaggg actctgaaaa tggagctttt tgttattcaa ggtctcggct gcctggatct gcaacttacc ccgtcagact gaccaaccca gtgtcccggt tcatgcaggt gcgctcgttg cagtacctgt gtcgttttgt tatacgtcag tataccagaa tagacttaat tcagaaactg cctttgccaa acaaaatgaa ggattattta caggagaagc Protein function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5- SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor. [The UniProt Consortium]