SMG7 (Vector pUC, Accession No. BC036381)

Length: 3537 Sequence: atgagcctgc agagcgcgca gtacctccgg caggcagaag tcctgaaggc tgacatgaca gattctaagc tgggtccagc tgaagtctgg acatccaggc aggctctgca ggacctgtac cagaaaatgc tagttaccga tttggaatac gctttagaca agaaagtaga acaggatctc tggaatcacg cctttaagaa tcagatcaca acactacaag gccaggcaaa gaatcgagca aatccgaatc ggagtgaagt tcaggcaaac ctttctctgt tcctagaggc agctagtggc ttctatactc agttattaca agaactgtgt acagtattta atgtagattt accatgccgt gtgaagtctt cccaattggg aattatcagc aataaacaga cgcataccag cgccatagtg aagccacagt ctagctcctg ttcctatatc tgccagcact gcctcgtcca ccttggagac attgctcgat acagaaacca gaccagccag gcagagtcct actataggca tgcagctcag cttgtcccct ccaatggtca gccttataat cagttggcta tcttagcttc ttccaaagga gaccatctga ccacaatttt ctactactgc agaagcattg ctgtgaagtt ccctttccca gctgcctcca ctaatctgca aaaagcactt tctaaagcac tggaaagccg agatgaggtg aaaaccaagt ggggtgtttc tgacttcatc aaggccttta ttaaattcca cggtcatgtg tacctgagta agagcttgga aaagttgagc cctcttcgag agaaattgga agaacagttt aagaggctgc tattccaaaa agctttcaac tctcagcagt tagttcatgt cactgtcatt aacctgtttc aacttcatca ccttcgtgac tttagcaatg aaaccgagca gcacacttat agccaagatg agcagctatg ttggacacag ttgctggccc tctttatgtc ttttctcggc atcctgtgca agtgtcctct acagaatgag tctcaggagg agtcctacaa tgcctatcct cttccagcag tcaaggtctc catggactgg ctaagactca gacccagggt ctttcaggag gcagtggtgg atgaaagaca gtacatttgg ccctggttga tttctcttct gaatagtttc catccccatg aagaggacct ctcaagtatt agtgcgacac cacttccaga ggagtttgaa ttacaaggat ttttggcatt gagaccttct ttcaggaact tggatttttc caaaggtcac cagggtatta caggggacaa agaaggccag caacgacgaa tacgacagca acgcttgatc tctataggca aatggattgc tgataatcag ccaaggctga ttcagtgtga aaatgaggta gggaaattgt tgtttatcac agaaatccca gaattaatac tggaagaccc cagtgaagcc aaagagaacc tcattctgca agaaacatct gtgatagagt cgctggctgc agatgggagc ccagggctaa aatcagtgct atctacaagc cgaaatttaa gcaacaactg tgacacagga gagaagccag tggttacctt caaagaaaac attaagacac gagaagtgaa cagagaccaa ggaagaagtt ttcctcccaa agaggtaaaa tcccagacag aactaagaaa gactccagtg tctgaagcca gaaaaacacc tgtaactcaa accccaactc aagcaagtaa ctcccagttc atccccattc atcaccctgg agccttccct cctcttccca gcaggccagg gtttccgccc ccaacatatg ttatcccccc gcctgtggca ttttctatgg gctcaggtta caccttccca gctggtgttt ctgtcccagg aacctttctt cagcctacag ctcactctcc agcaggaaac caggtgcaag ctgggaaaca gtcccacatt ccttacagcc agcaacggcc ctctggacca gggccaatga accagggacc tcaacaatca cagccacctt cccagcaacc ccttacatct ttaccagctc agccaacagc acagtctaca agccagctgc aggttcaagc tctaactcag caacaacaat cccctacaaa agctgtgccg gctttgggga aaagcccgcc tcaccactct ggattccagc agtatcaaca ggcagatgcc tccaaacagc tgtggaatcc ccctcaggtt caaggcccat tagggaaaat tatgcctgtg aaacagccct actaccttca gacccaagac cccataaaac tgtttgagcc gtcattgcaa cctcctgtaa tgcagcagca gcctctagaa aaaaaaatga agccttttcc catggagcca tataaccata atccctcaga agtcaaggtc ccagaattct actgggattc ttcctacagc atggctgata acagatctgt aatggcacag caagcaaaca tagaccgcag gggcaaacgg tcaccaggaa tcttccgtcc agagcaggat cctgtaccca gaatgccgtt tgaggacccc aagagctccc ctctgcttcc tccggacctg ttaaagagtc tggctgcctt ggaggaagag gaagagctga ttttttctaa cactcctgat ctttacccgg ctctgctggg gcctctcgcc tctcttcctg gacgaagcct ttttaaatcc ttattggaga agccctcaga gctcatgtca cattcatcct ctttcctgtc cctcaccgga ttctctctca atcaggaaag atacccaaat aatagtatgt tcaatgaggt atatgggaaa aacctgacat ccagctccaa agcagaactc agtccctcaa tggcccccca ggaaacatct ctgtattccc tttttgaagg gactccgtgg tctccatcac ttcctgccag ttcagatcat tcaacaccag ccagccagtc tcctcattcc tctaacccaa gcagcctacc cagctctcct ccaacacaca accataattc tgttccattc tccaattttg gacccattgg gactccagat aacagggata gaaggactgc agatcggtgg aaaactgata agccagccat gggtgggttt ggcattgatt atctctcagc aacgtcatcc tctgagagca gttggcatca ggccagcact ccgagtggca cctggacagg ccatggccct tccatggagg attcctctgc tgtcctcatg gaaagcctaa agaagcaaca gcatggggtc cagcagttgg ggcccaaaag acagtctgaa gaggaaggaa gcagcagtat ctgcgtagcc cacagagggc ccaggcccct gcccagctgc agtctcccag cctccacttt cagagtgaaa ttcaaggcag cacggacatg tgcccatcag gcacagaaga aaacacgacg tcgtccattt tggaagagac gaaagaaagg Protein function: Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. [The UniProt Consortium]