SMG6 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 1536 Sequence: atggagacat tccctgcagt ggctgagaag gtcctcaagg agttccaggt gttactgcag cacagcccct ctcccattgg aagtacccgc atgctgcagc ttatgaccat caatatgttt gcagtacaca actcccagct gaaagactgc ttctcggagg agtgccgctc tgtgatccag gaacaagccg cagctctggg cttggccatg ttttctctac tggtccgccg ctgcacctgc ttacttaagg agtccgccaa agctcagctg tcctctcctg aggaccagga tgaccaagac gacatcaagg tgtcttcctt tgtcccggac ctgaaggagc tgctccccag tgtcaaagtc tggtcagatt ggatgctcgg ctacccggac acctggaatc ctcctcccac atccctggat ctgccctcgc atgttgctgt ggatgtatgg tcgacgctgg ctgatttctg taacatactg actgcagtga atcagtctga ggtgccactg tacaaggacc cggatgatga cctcaccctt cttatcctgg aagaggatcg gcttctctcg ggctttgtcc ccttgctggc tgcccctcag gacccctgct acgtggagaa aacctcggat aaggttattg cagctgactg caaaagggtc acagtgctga agtattttct ggaagccctt tgtggacaag aagagcctct gctggcattc aagggtggaa agtatgtgtc agtggcaccc gtcccagaca ccatgggaaa ggaaatggga agccaagagg gaacacgact ggaagatgag gaggaggatg tggtgattga agactttgag gaagattcag aggctgaagg cagcggaggc gaggatgaca tcagggagct tcgggccaag aagctggctc tggccaggaa gatagctgag cagcagcgtc gccaggaaaa gatccaggct gtcctggagg accacagtca gatgaggcag atggagctcg aaatcagacc tttgttcctc gtaccagaca ccaacggctt cattgaccac ctggccagtc tggcgcggct gctggagagc aggaagtaca tcctggtggt gcccctcatc gtgatcaatg agctggacgg cctggccaag gggcaggaga cagaccaccg ggctgggggc tacgcccgtg tggtacaaga gaaggcccgc aagtccatcg agttcctcga gcagcgattc gagagtcggg actcttgcct gcgagccctg accagccgtg gcaatgaact cgaatccatc gccttccgca gtgaggacat cactggccag ctgggtaaca acgatgatct catcctgtcc tgctgcctcc actactgcaa agacaaggct aaggacttca tgcccgccag caaagaggag ccaatccggc tactgcggga ggtggtgctg ttgacggatg accggaacct gcgtgtgaag gcgctcacaa ggaatgttcc tgtacgggac atcccagcct tcctcacgtg ggcccaggtg Protein function: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini (PubMed:19179534). May have a general role in telomere regulation (PubMed:12676087, PubMed:12699629). Promotes in vitro the ability of TERT to elongate telomeres (PubMed:12676087, PubMed:12699629). Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization (PubMed:12676087, PubMed:12699629). Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER) (PubMed:12676087, PubMed:12699629). [The UniProt Consortium]