SLC7A8 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1608 Sequence: atggaagaag gagccaggca ccgaaacaac accgaaaaga aacacccagg tgggggcgag tcggacgcca gccccgaggc tggttccgga gggggcggag tagccctgaa gaaagagatc ggattggtca gtgcctgtgg tatcatcgta gggaacatca tcggctctgg aatctttgtc tcgccaaagg gagtgctgga gaatgctggt tctgtgggcc ttgctctcat cgtctggatt gtgacgggct tcatcacagt tgtgggagcc ctctgctatg ctgaactcgg ggtcaccatc cccaaatctg gaggtgacta ctcctatgtc aaggacatct tcggaggact ggctgggttc ctgaggctgt ggattgctgt gctggtgatc taccccacca accaggctgt catcgccctc accttctcca actacgtgct gcagccgctc ttccccacct gcttcccccc agagtctggc cttcggctcc tggctgccat ctgcttattg ctcctcacat gggtcaactg ttccagtgtg cggtgggcca cccgggttca agacatcttc acagctggga agctcctggc cttggccctg attatcatca tggggattgt acagatatgc aaaggagagt acttctggct ggagccaaag aatgcatttg agaatttcca ggaacctgac atcggcctcg tcgcactggc tttccttcag ggctcctttg cctatggagg ctggaacttt ctgaattacg tgactgagga gcttgttgat ccctacaaga accttcccag agccatcttc atctccatcc cactggtcac atttgtgtat gtctttgcca atgtcgctta tgtcactgca atgtcccccc aggagctgct ggcatccaac gccgtcgctg tgacttttgg agagaagctc ctaggagtca tggcctggat catgcccatt tctgttgccc tgtccacatt tggaggagtt aatgggtctc tcttcacctc ctctcggctg ttcttcgctg gagcccgaga gggccacctt cccagtgtgt tggccatgat ccacgtgaag cgctgcaccc caatcccagc cctgctcttc acatgcatct ccaccctgct gatgctggtc accagtgaca tgtacacact catcaactac gtgggcttca tcaactacct cttctatggg gtcacggttg ctggacagat agtccttcgc tggaagaagc ctgatatccc ccgccccatc aagatcaacc tgctgttccc catcatctac ttgctgttct gggccttcct gctggtcttc agcctgtggt cagagccggt ggtgtgtggc attggcctgg ccatcatgct gacaggagtg cctgtctatt tcctgggtgt ttactggcaa cacaagccca agtgtttcag tgacttcatt gagctgctaa ccctggtgag ccagaagatg tgtgtggtcg tgtaccccga ggtggagcgg ggctcaggga cagaggaggc taatgaggac atggaggagc agcagcagcc catgtaccaa cccactccca cgaaggacaa ggacgtggcg gggcagcccc Protein function: Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney. [The UniProt Consortium]