SLC47A1 (Vector pENTR223.1, Accession No. BC058882)

Length: 873 Sequence: atggaagctc ctgaggagcc cgcgccagtg cgcggaggcc cggaggccac ccttgaggtc cgtgggtcgc gctgcttgcg gctgtccgcc ttccgagaag agctgcgggc gctcttggtc ctggctggcc ccgcgttctt ggttcagctg atggtgttcc tgatcagctt cataagctcc gtgttctgtg gccacctggg caagctggag ctggatgcag tcacgctggc aatcgcggtt atcaatgtca ctggtgtctc agtgggattc ggcttatctt ctgcctgtga caccctcatc tcccagacgt acgggagcca gaacctgaag cacgtgggcg tgatcctgca gcggagtgcg ctcgtcctgc tcctctgctg cttcccctgc tgggcgctct ttctcaacac ccagcacatc ctgctgctct tcaggcagga cccagatgtg tccaggctta cccagaccta tgtcacgatc ttcattccag ctcttcctgc aacctttctt tatatgttac aagttaaata tttgctcaac cagggaattg tactgcccca gatcgtaact ggagttgcag ccaaccttgt caatgccctc gccaactatc tgtttctcca tcaactgcat cttggggtga taggctctgc actggcaaac ttgatttccc agtacaccct ggctctactc ctctttctct acatcctcgg gaaaaaactg catcaagcta catggggagg ctggtccctc gagtgcctgc aggactgggc ctccttcctc cgcctggcca tccccagcat gctcatgctg tgcatggagt ggtgggccta tgaggtcggg agcttcctca gtggtctgta tgaggatgga Protein function: Solute transporter for tetraethylammonium (TEA), 1-methyl-4- phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium), a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes. [The UniProt Consortium]