SGK3 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 1491 Sequence: atgcaaagag atcacaccat ggactacaag gaaagctgcc caagtgtaag cattcccagc tccgatgaac acagagagaa aaagaagagg tttactgttt ataaagttct ggtttcagtg ggaagaagtg aatggtttgt cttcaggaga tatgcagagt ttgataaact ttataacact ttaaaaaaac agtttcctgc tatggccctg aagattcctg ccaagagaat atttggtgat aattttgatc cagattttat taaacaaaga cgagcaggac taaacgaatt cattcagaac ctagttaggt atccagaact ttataaccat ccagatgtca gagcattcct tcaaatggac agtccaaaac accagtcaga tccatctgaa gatgaggatg aaagaagttc tcagaagcta cactctacct cacagaacat caacctggga ccgtctggaa atcctcatgc caaaccaact gactttgatt tcttaaaagt tattggaaaa ggcagctttg gcaaggttct tcttgcaaaa cggaaactgg atggaaaatt ttatgctgtc aaagtgttac agaaaaaaat agttctcaac agaaaagagc aaaaacatat tatggctgaa cgtaatgtgc tcttgaaaaa tgtgaaacat ccgtttttgg ttggattgca ttattccttc caaacaactg aaaagcttta ttttgttctg gattttgtta atggagggga gctttttttc cacttacaaa gagaacggtc ctttcctgag cacagagcta ggttttacgc tgctgaaatt gctagtgcat tgggttactt acattccatc aaaatagtat acagagactt gaaaccagaa aatattcttt tggattcagt aggacatgtt gtcttaacag attttgggct ttgtaaagaa ggaattgcta tttctgacac cactaccaca ttttgtggga caccagagta tcttgcacct gaagtaatta gaaaacagcc ctatgacaat actgtagatt ggtggtgcct tggggctgtt ctgtatgaaa tgctgtatgg attgcctcct ttttattgcc gagatgttgc tgaaatgtat gacaatatcc ttcacaaacc cctaagtttg aggccaggag tgagtcttac agcctggtcc attctggaag aactcctaga aaaagacagg caaaatcgac ttggtgccaa ggaagacttt cttgaaattc agaatcatcc tttttttgaa tcactcagct gggctgacct tgtacaaaag aagattccac caccatttaa tcctaatgtg gctggaccag atgatatcag aaactttgac acagcattta cagaagaaac agttccatat tctgtgtgtg tatcttctga ctattctata gtgaatgcca gtgtattgga ggcagatgat gcattcgttg gtttctctta tgcacctcct tcagaagact tatttttgtg Protein function: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca(2+) channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na(+)/dicarboxylate cotransporter: SLC13A2/NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes. [The UniProt Consortium]