SEC24C (Vector pUC, Accession No. BC018928)

Length: 3285 Sequence: atgaacgtca accagtcagt tccacctgtg ccaccatttg ggcagcccca gcccatctac ccagggtatc atcagtccag ctatggtggg caatcagggt ccacagcccc cgccattccc tatggagcct acaatggccc agtaccaggc tatcagcaaa cacctcccca aggtatgtca agagccccac cttcctcggg ggcacctcca gcctcaacag cacaggctcc ttgtggccag gctgcatatg gccagtttgg ccaaggagat gtacagaatg ggccaagctc cactgttcag atgcaaaggc tgcctgggtc tcagtcattt gggtccccat tggcccctgt gggcaaccag ccacctgtgc ttcagcccta tggccctccc ccgacaagtg cacaggtggc tacgcagctg tctggaatgc agatcagcgg tgctgtggcc ccagcccctc cttcttcagg gctgggcttt ggcccaccaa catcgctggc ttcagcctca ggaagtttcc ctaactctgg tctgtatggc tcctatcctc agggccaggc tcctcccctt agccaggccc aaggtcatcc tgggatccag actccccagc gatctgcccc atcacaggcc tccagcttca cacccccagc ttcagggggt cctcggctgc cttcgatgac tggtccactc ctgcctggac agagttttgg agggccctca gtgagccagc ccaaccatgt gtcttcacct cctcaagctc tgccccctgg cacccagatg actgggcccc tgggaccact gccacctatg cactccccgc agcagccagg ctatcagccc caacaaaatg gttccttcgg accagcccgg ggccctcagt ctaattatgg aggcccctac ccagcagcac ccacctttgg cagtcagcct gggcctcctc agccactgcc tcctaagcgc ctggaccctg atgccatccc aagccctatt caggtcattg aagatgacag gaacaaccgg ggtacagagc catttgttac tggagtacgg ggccaggtgc cacccttagt cactaccaac ttcctggtga aagaccaagg gaatgcaagt ccccgataca tccgatgtac atcctataat atcccttgca catctgacat ggctaagcag gctcaggtgc ccctggcagc agtcatcaaa ccgctggcaa ggctgccccc agaggaggct tcaccgtatg ttgtggacca tggggaatct ggccctttgc gctgcaaccg ctgcaaagca tacatgtgtc ccttcatgca gttcattgaa ggagggaggc gtttccagtg ctgtttttgc agctgtatca atgatgttcc cccccagtat tttcagcacc tggatcatac cggcaaacgt gtggatgctt atgaccgccc tgagctatcc ctgggctctt atgaattctt ggccactgta gattactgca agaacaataa gttccccagc cctcctgcct ttatcttcat gattgacgtc tcctacaatg ccatcaggac tggtcttgtt aggctcctct gtgaggagct caagtcactg ttagactttc tacctaggga gggtggggca gaagagtcag caatccgcgt tggctttgtc acctacaata aggtgctcca cttctataat gtgaagagct cattggccca gccacagatg atggttgtgt ctgatgtggc tgacatgttt gtgccactgc tggatggctt cctggtcaac gtcaatgagt ctcgggcagt tatcaccagc ttattggatc agattccaga aatgtttgca gacacaaggg aaacagagac agtatttgta ccagttatcc aggctggaat ggaggctctg aaggctgctg agtgtgcagg gaagctcttt ctattccata catccctgcc cattgcagag gccccaggga aactgaagaa cagagatgac aggaagctga tcaatacaga caaggagaag actctgttcc agcctcagac aggtgcctat cagaccctgg ccaaagagtg tgtggcccaa ggctgctgtg tagatctctt tctcttccct aaccagtatg tggatgtggc cacactctct gttgtgcccc agctcactgg tggctctgtc tacaaatatg cttcctttca ggtggagaac gaccaggagc ggttcctgag tgacctgcgt cgtgatgtcc agaaggttgt tggctttgat gctgtgatgc gggtccggac aagcactggt atccgtgctg tagatttctt tggagctttc tacatgagca acacgacaga tgtggagctg gctgggctag atggggacaa aacagtgact gtggagttca agcatgacga tcggctcaat gaagagagcg gagctctcct gcagtgtgcc ctgctttaca ccagctgtgc agggcagcgt cggctccgca tccataatct ggccctgaac tgctgcaccc agctggctga tctatatcga aactgtgaga ctgacacgct catcaactac atggccaagt ttgcatatcg gggagtcctg aatagccctg tgaaggctgt tcgtgacacg ctcatcaccc agtgtgccca gatcctggcc tgttacagaa agaactgtgc tagcccctcc tctgcaggac agttgatcct tcctgagtgc atgaagctac tcccagttta cctgaactgt gtgttgaaga gtgatgtcct gcagcctgga gctgaagtca ctactgatga ccgtgcctat gtccgacagc tagttacctc catggatgtg actgagacca atgtcttctt ctaccctcgg ctcttacctt tgacaaagtc tcccgttgag agtactaccg aaccaccagc agttcgagcc tctgaagagc gtctaagcaa tggggatata tatttactgg agaatgggct caacctcttc ctctgggtgg gagcaagcgt ccaacagggt gttgtccaga gccttttcag cgtctcctcc ttcagtcaga tcaccagtgg tttgagtgtt ctgccagttc tggataatcc actgtccaag aaggttcgag gcctcattga tagcttacgg gcacagagat cccggtacat gaagcttacc gtggtgaaac aggaagacaa gatggagatg ctgttcaagc acttcctggt ggaagacaag agtctgagtg ggggagcatc ttatgtggac tttctctgtc atatgcacaa ggagattcgg cagctactga Protein function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:10214955, PubMed:17499046, PubMed:18843296, PubMed:20427317). Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B (PubMed:17499046, PubMed:20427317, PubMed:18843296). May more specifically package GPI-anchored proteins through the cargo receptor TMED10 (PubMed:20427317). May also be specific for IxM motif- containing cargos like the SNAREs GOSR2 and STX5 (PubMed:18843296). [The UniProt Consortium]