SEC24A (Vector pUC, Accession No. BC019341)

Length: 1842 Sequence: atgtcccagc cgggaatacc ggcctccggc ggcgccccag ccagcctcca ggcccagaac ggagccgcct tggcctcggg gtctccctac accaacggtc ctgtccaaaa tgcattgctg tcttcacaag agtcagtgag ccaaggatac aatttccagc ttccaggatc ctaccctcat ccaataccag caaagacttt gaatccagtc tctggacagt ctaactatgg tggttctcag ggatctgggc agactcttaa tagaccacct gtggcctcta atccagtgac accttcgctt catagtggtc ctgctccccg aatgccatta cctgcttctc agaacccagc tactacacca atgccttcta gtagctttct tcctgaagcc aacctgccac cacctttgaa ttggcaatat aactatccat ccacagcctc acaaacaaac cattgtcctc gtgcatcatc ccaaccaact gtatctggaa atacaagttt aaccacaaat catcaatatg tttcttctgg atatccttca cttcaaaata gcttcataaa gtcaggtcct tctgtacctc ccttagtgaa tccacctctg cctacaactt ttcaaccagg agctcctcat gggccccctc cagctggagg cccaccccca gtgagggccc tcacgcccct gacatcatca tatagagatg taccccagcc cttatttaat tcagctgtca accaagaagg tattacatca aataccaata acggatctat ggtggtccac agtagttacg acgagattga aggaggtggc ttattggcaa caccacagct tactaacaag aatcccaaaa tgagccgaag tgttggatat tcatatccct ccttaccacc tggttatcag aacataacac cacctggtgc aactggagta ccaccctctt ccttgaatta cccaagtggg ccacaagcct ttactcagac tcccttaggt gctaatcatt taaccacaag catgagtgga ttaagtctac aaccagaggg tctaagagtt gtcaatcttc ttcaagaaag aaacatgctt ccgtcaacac ctttgaagcc tccagttcca aatttgcatg aagacatcca gaaactcaac tgtaacccag agttatttcg atgcacgctg actagcattc ctcagatgca ggccttattg aataaagcca aacttccttt ggggctgctg cttcatcctt tcaaagactt agtgcaattg cctgtggtta cctccagtac aattgtgaga tgccgttcat gcaggacgta catcaatcct ttcgtcagct ttcttgatca aaggagatgg aagtgtaact tatgttatcg agtcaatgat gttcctgaag aattcttgta caaccctttg accagagttt atggagaacc tcacagaaga ccagaagttc aaaatgctac tattgagttt atggctcctt cagaatacat gttacgacca cctcagcctc cagtgtatct ctttgtattt gatgtgtctc acaatgcagt cgaaactgga tacttgaatt cagtttgcca gagtttgtta gacaatctgg atttgcttcc tggcaacact agaacaaaaa ttggcttcat aacatttgac agtacaatcc atttctacgg tcttcaggaa agtctctctc aacctcagat gctaatagtt tcagatattg aagatgtttt tatacctatg ccagagaact tattagtaaa cttaaatgaa agtaaagaga gtgtcattgg ggtcagttca gaagaaactc ttattacctg cctggaaatt gccatgagat Protein function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:20427317, PubMed:17499046, PubMed:18843296). Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes (PubMed:17499046, PubMed:18843296). [The UniProt Consortium]