SCUBE3 (Vector pUC, Accession No. BC052263)

Length: 2979 Sequence: atgggctcgg ggcgcgtacc cgggctctgc ctgcttgtcc tgctggtcca cgcccgcgcc gcccagtaca gcaaagccgc gcaagatgtg gatgagtgtg tggaggggac tgacaactgc cacatcgatg ctatctgcca gaacaccccg aggtcataca agtgcatctg caagtctggc tacacagggg acggcaaaca ctgcaaagac gtggatgagt gcgagcgaga ggataatgca ggttgtgtgc atgactgtgt caacatccct ggcaattacc ggtgtacctg ctatgatgga ttccacctgg cacatgacgg acacaactgt ctggatgtgg acgagtgtgc cgagggcaac ggcggctgtc agcagagctg tgtcaacatg atgggcagct atgagtgcca ctgccgggaa ggcttcttcc tcagcgacaa ccagcatacc tgtatccagc ggccagaagg aatgaactgc atgaacaaga accacggctg tgcccacatt tgccgggaga cacccaaggg gggtattgcc tgtgaatgcc gtcctggctt tgagcttacc aagaaccaac gggactgtaa attgacatgc aactatggta acggcggctg ccagcacacg tgtgatgaca cagagcaggg tccccggtgc ggctgccata tcaagtttgt gctccatacc gacgggaaga catgcatcga gacctgtgct gtcaacaacg ggggctgtga cagtaagtgc catgatgcag cgattggtgt ccactgcacc tgccctgtgg gcttcatgct gcagccagac aggaagacgt gcaaagatat agatgagtgc cgcttaaaca acgggggctg tgaccatatt tgccgcaaca cagtgggcag cttcgaatgc agttgcaaga aaggctataa gcttctcatc aatgagagga actgccagga tatagacgag tgttcctttg atcgaacctg tgaccacata tgtgtcaaca caccaggaag cttccagtgt ctctgccatc gtggctacct gttgtatggt atcacccact gtggggatgt ggatgaatgc agcatcaacc ggggaggttg ccgctttggc tgcatcaaca ctcctggcag ctaccagtgt acctgcccag caggccaggg tcggctgcac tggaatggca aagattgcac agagccactg aagtgtcagg gcagtcctgg ggcctcgaaa gccatgctca gctgcaaccg gtctggcaag aaggacacct gtgccctgac ctgtccctcc agggcccgat ttttgccaga gtctgagaat ggcttcacgg tgagctgtgg gacccccagc cccagggctg ctccagcccg agctggccac aatgggaaca gcaccaactc caaccactgc catgaggctg cagtgctgtc cattaaacaa cgggcctcct tcaagatcaa ggatgccaaa tgccgtttgc acctgcgaaa caaaggcaaa acagaggagg ctggcagaat cacagggcca ggtggtgccc cctgctctga atgccaggtc accttcatcc accttaagtg tgactcctct cggaagggca agggccgacg ggcccggacc cctccaggca aagaggtcac aaggctcacc ctggaactgg aggcagaggt cagagccgaa gaaaccacag ccagctgtgg gctgccctgc ctccgacagc gaatggaacg gcggctgaaa ggatccctga agatgctcag aaagtccatc aaccaggacc gcttcctgct gcgcctggca ggccttgatt atgagctggc ccacaagccg ggcctggtag ccggggagcg agcagagccg atggagtcct gtaggcccgg gcagcaccgt gctgggacca agtgtgtcag ctgcccgcag ggaacgtatt accacggcca gacggagcag tgtgtgccat gcccagcggg caccttccag gagagagaag ggcagctctc ctgcgacctt tgccctggga gtgatgccca cgggcctctt ggagccacca acgtcaccac gtgtgcaggt cagtgcccac ctggccaaca ctctgtagat gggttcaagc cctgtcagcc atgcccacgt ggcacctacc aacctgaagc aggacggacc ctatgcttcc cttgtggtgg gggcctcacc accaagcatg aaggggccat ttccttccaa gactgtgaca ccaaagtcca gtgctcccca gggcactact acaacaccag catccaccgc tgtattcgct gtgccatggg ctcctatcag cccgacttcc gtcagaactt ctgcagccgc tgtccaggaa acacaagcac agactttgat ggctctacca gtgtggccca atgcaagaat cgtcagtgtg gtggggagct gggtgagttc actggctata ttgagtcccc caactacccg ggcaactacc cagctggtgt ggagtgcatc tggaacatca accccccacc caagcgcaag atccttatcg tggtaccaga gatcttcctg ccatctgagg atgagtgtgg ggacgtcctc gtcatgagaa agaactcatc cccatcctcc attaccactt atgagacctg ccagacctac gagcgtccca ttgccttcac tgcccgttcc aggaagctct ggatcaactt caagacaagc gaggccaaca gcgcccgtgg cttccagatt ccctatgtta cctatgatga ggactatgag cagctggtag aagacattgt gcgagatggc cggctctatg cctctgaaaa ccaccaggag attttaaagg acaagaagct catcaaggcc ttctttgagg tgctagccca cccccagaac tacttcaagt acacagagaa acacaaggag atgctgccaa aatccttcat caagctgctc cgctccaaag tttccagctt cctgaggccc Protein function: Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression. [The UniProt Consortium]