SCNN1G (Vector pENTR223.1, Accession No. BC059391)

Length: 1950 Sequence: atggcacccg gagagaagat caaagccaaa atcaagaaga atctgcccgt gacgggccct caggcgccga ccattaaaga gctgatgcgg tggtactgcc tcaacaccaa cacccatggc tgtcgccgca tcgtggtgtc ccgcggccgt ctgcgccgcc tcctctggat cgggttcaca ctgactgccg tggccctcat cctctggcag tgcgccctcc tcgtcttctc cttctatact gtctcagttt ccatcaaagt ccacttccgg aagctggatt ttcctgcagt caccatctgc aacatcaacc cctacaagta cagcaccgtt cgccaccttc tagctgactt ggaacaggag accagagagg ccctgaagtc cctgtatggc tttccagagt cccggaagcg ccgagaggcg gagtcctgga actccgtctc agagggaaag cagcctagat tctcccaccg gattccgctg ctgatctttg atcaggatga gaagggcaag gccagggact tcttcacagg gaggaagcgg aaagtcggcg gtagcatcat tcacaaggct tcaaatgtca tgcacatcga gtccaagcaa gtggtgggat tccaactgtg ctcaaatgac acctccgact gtgccaccta caccttcagc tcgggaatca atgccattca ggagtggtat aagctacact acatgaacat catggcacag gtgcctctgg agaagaaaat caacatgagc tattctgctg aggagctgct ggtgacctgc ttctttgatg gagtgtcctg tgatgccagg aatttcacgc ttttccacca cccgatgcat gggaattgct atactttcaa caacagagaa aatgagacca ttctcagcac ctccatgggg ggcagcgaat atgggctgca agtcattttg tacataaacg aagaggaata caacccattc ctcgtgtcct ccactggagc taaggtgatc atccatcggc aggatgagta tcccttcgtc gaagatgtgg gaacagagat tgagacagca atggtcacct ctataggaat gcacctgaca gagtccttca agctgagtga gccctacagt cagtgcacgg aggacgggag tgacgtgcca atcaggaaca tctacaacgc tgcctactcg ctccagatct gccttcattc atgcttccag acaaagatgg tggagaaatg tgggtgtgcc cagtacagcc agcctctacc tcctgcagcc aactactgca actaccagca gcaccccaac tggatgtatt gttactacca actgcatcga gcctttgtcc aggaagagct gggctgccag tctgtgtgca aggaagcctg cagctttaaa gagtggacac taaccacaag cctggcacaa tggccatctg tggtttcgga gaagtggttg ctgcctgttc tcacttggga ccaaggccgg caagtaaaca aaaagctcaa caagacagac ttggccaaac tcttgatatt ctacaaagac ctgaaccaga gatccatcat ggagagccca gccaacagta ttgagatgct tctgtccaac ttcggtggcc agctgggcct gtggatgagc tgctctgttg tctgcgtcat cgagatcatc gaggtcttct tcattgactt cttctctatc attgcccgcc gccagtggca gaaagccaag gagtggtggg cctggaaaca ggctccccca tgtccagaag ctccccgtag cccacagggc caggacaatc cagccctgga tatagacgat gacctaccca ctttcaactc tgctttgcac ctgcctccag ccctaggaac ccaagtgccc ggcacaccgc cccccaaata caataccttg cgcttggaga gggccttttc caaccagctc acagataccc agatgctgga Protein function: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. [The UniProt Consortium]