SARS (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 1545 Sequence: atggtgctgg atctggattt gtttcgggtg gataaaggag gggacccagc cctcatccga gagacgcagg agaagcgctt caaggacccg ggactagtgg accagctggt gaaggcagac agcgagtggc gacgatgtag atttcgggca gacaacttga acaagctgaa gaacctatgc agcaagacaa tcggagagaa aatgaagaaa aaagagccag tgggagatga tgagtctgtc ccagagaatg tgctgagttt cgatgacctt actgcagacg ctttagctaa cctgaaagtc tcacaaatca aaaaagtccg actcctcatt gatgaagcca tcctgaagtg tgacgcggag cggataaagt tggaagcaga gcggtttgag aacctccgag agattgggaa ccttctgcac ccttctgtac ccatcagtaa cgatgaggat gtggacaaca aagtagagag gatttggggt gattgtacag tcaggaagaa gtactctcat gtggacctgg tggtgatggt agatggcttt gaaggcgaaa agggggccgt ggtggctggg agtcgagggt acttcttgaa gggggtcctg gtgttcctgg aacaggctct catccagtat gcccttcgca ccttgggaag tcggggctac attcccattt ataccccctt tttcatgagg aaggaggtca tgcaggaggt ggcacagctc agccagtttg atgaagaact ttataaggtg attggcaaag gcagtgaaaa gtctgatgac aactcctatg atgagaagta cctgattgcc acctcagagc agcccattgc tgccctgcac cgggatgagt ggctccggcc ggaggacctg cccatcaagt atgctggcct gtctacctgc ttccgtcagg aggtgggctc ccatggccgt gacacccgtg gcatcttccg agtccatcag tttgagaaga ttgaacagtt tgtgtactca tcaccccatg acaacaagtc atgggagatg tttgaagaga tgattaccac cgcagaggag ttctaccagt ccctggggat tccttaccac attgtgaata ttgtctcagg ttctttgaat catgctgcca gtaagaagct tgacctggag gcctggtttc cgggctcagg agccttccgt gagttggtct cctgttctaa ttgcacggat taccaggctc gccggcttcg aatccgatat gggcaaacca agaagatgat ggacaaggtg gagtttgtcc atatgctcaa tgctaccatg tgcgccacta cccgtaccat ctgcgccatc ctggagaact accagacaga gaagggcatc actgtgcctg agaaattgaa ggagttcatg ccgccaggac tgcaagaact gatccccttt gtgaagcctg cgcccattga gcaggagcca tcaaagaagc agaagaagca acatgagggc agcaaaaaga aagcagcagc aagagacgtc accctagaaa acaggctgca gaacatggag gtcaccgatg Protein function: Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser) (PubMed:22353712, PubMed:24095058, PubMed:9431993, PubMed:26433229, PubMed:28236339). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (PubMed:9431993, PubMed:26433229, PubMed:28236339). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC (PubMed:24940000). Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16). Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA (PubMed:19423848, PubMed:19423847, PubMed:24940000). [The UniProt Consortium]