SAP30L (Vector pUC, Accession No. BC009829)

Length: 552 Sequence: atgaacggct tcagcacgga ggaggacagc cgcgaagggc cccccgccgc cccagctgcc gccgccccgg gctacggcca gagctgctgc ctcatcgagg acggcgagcg ctgcgtccgg cccgcgggca acgcctcctt cagcaagagg gtccagaaga gcatctcgca gaagaaactc aagctggaca tcgacaagag cgtaaggcac ctatatatct gtgattttca caaaaatttc atccagagtg tccgaaataa aaggaagagg aagacaagtg acgatggcgg agattctccc gagcacgaca ctgacattcc tgaggttgat ctgttccagc tgcaggtgaa caccctacga cgttataaac gacactacaa gttgcagacc agaccaggct tcaataaggc ccagttagca gaaactgtga gtcgacactt caggaacata cctgtgaatg aaaaagagac ccttgcctac ttcatctaca tggtgaagag taacaagagt agactggacc agaaatcgga gggtggcaag cagcttgagt Protein function: [Isoform 1]: Functions as transcription repressor, probably via its interaction with histone deacetylase complexes (PubMed:16820529, PubMed:18070604). Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus (PubMed:16820529). Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA (PubMed:19015240). Binds phosphoinositol phosphates (phosphoinositol 3- phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import (PubMed:19015240, PubMed:26609676). [The UniProt Consortium]