RTN4RL2 (Vector pUC, Accession No. BC113673)

Length: 1263 Sequence: atgctgcccg ggctcaggcg cctgctgcaa gctcccgcct cggcctgcct cctgctgatg ctcctggccc tgcccctggc ggcccccagc tgccccatgc tctgcacctg ctactcatcc ccgcccaccg tgagctgcca ggccaacaac ttctcctctg tgccgctgtc cctgccaccc agcactcagc gactcttcct gcagaacaac ctcatccgca cgctgcggcc aggcaccttt gggtccaacc tgctcaccct gtggctcttc tccaacaacc tctccaccat ctacccgggc actttccgcc acttgcaagc cctggaggag ctggacctcg gtgacaaccg gcacctgcgc tcgctggagc ccgacacctt ccagggcctg gagcggctgc agtcgctgca tttgtaccgc tgccagctca gcagcctgcc cggcaacatc ttccgaggcc tggtcagcct gcagtacctc tacctccagg agaacagcct gctccaccta caggatgact tgttcgcgga cctggccaac ctgagccacc tcttcctcca cgggaaccgc ctgcggctgc tcacagagca cgtgtttcgc ggcctgggca gcctggaccg gctgctgctg cacgggaacc ggctgcaggg cgtgcaccgc gcggccttcc gcggcctcag ccgcctcacc atcctctacc tgttcaacaa cagcctggcc tcgctgcccg gcgaggcgct cgccgacctg ccctcgctcg agttcctgcg gctcaacgct aacccctggg cgtgcgactg ccgcgcgcgg ccgctctggg cctggttcca gcgcgcgcgc gtgtccagct ccgacgtgac ctgcgccacc cccccggagc gccagggccg agacctgcgc gcgctccgcg aggccgactt ccaggcgtgt ccgcccgcgg cacccacgcg gccgggcagc cgcgcccgcg gcaacagctc ctccaaccac ctgtacgggg tggccgaggc cggggcgccc ccagccgatc cctccaccct ctaccgagat ctgcctgccg aagactcgcg ggggcgccag ggcggggacg cgcctactga ggacgactac tgggggggct acgggggtga ggaccagcga ggggagcaga tgtgccccgg cgctgcctgc caggcgcccc cggactcccg aggccctgcg ctctcggccg ggctccccag ccctctgctt tgcctcctgc tcctggtgcc ccaccacctc Protein function: Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG. Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis, protection against apoptosis is probably mediated by MAG. Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed:22325200). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed:22325200). [The UniProt Consortium]