RTN3 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 711 Sequence: atggcggagc cgtcggcggc cactcagtcc cattccatct cctcgtcgtc cttcggagcc gagccgtccg cgcccggcgg cggcgggagc ccaggagcct gccccgccct ggggacgaag agctgcagct cctcctgtgc ggtgcacgat ctgattttct ggagagatgt gaagaagact gggtttgtct ttggcaccac gctgatcatg ctgctttccc tggcagcttt cagtgtcatc agtgtggttt cttacctcat cctggctctt ctctctgtca ccatcagctt caggatctac aagtccgtca tccaagctgt acagaagtca gaagaaggcc atccattcaa agcctacctg gacgtagaca ttactctgtc ctcagaagct ttccataatt acatgaatgc tgccatggtg cacatcaaca gggccctgaa actcattatt cgtctctttc tggtagaaga tctggttgac tccttgaagc tggctgtctt catgtggctg atgacctatg ttggtgctgt ttttaacgga atcacccttc taattcttgc tgaactgctc attttcagtg tcccgattgt ctatgagaag tacaagaccc agattgatca ctatgttggc atcgcccgag atcagaccaa gtcaattgtt gaaaagatcc aagcaaaact ccctggaatc gccaaaaaaa aggcagaata Protein function: May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules (PubMed:25612671). [The UniProt Consortium]