RPUSD4 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1134 Sequence: atggcggcgc ccaggtggag cgcgtcgggc ccctggatcc ggggaaacgg ccaaggttgc gggagtctct tcactctcgt ctcaaagcca ttttgtgccg ctgccgctgc ctctacggcc ataaatgccc agagattagc ggagaagctc cgagcccaga aacgggaaca agacacaaag aaggagccgg tgtccacaaa cgctgttcag cggagagtgc aagaaatagt gcggttcaca cggcagctgc agcgagtcca ccccaacgtg cttgctaagg cactgacccg aggaattctc caccaggaca agaaccttgt ggtcatcaat aagccctacg gtctccctgt gcatggtggc cctggggtcc agctctgcat cactgatgta ctacctatcc tggcaaagat gcttcatggc cacaaggcag agcccttgca tctgtgccac cggctggaca aggaaaccac aggtgtaatg gtgttggctt gggacaagga catggcacat caagtccaag agttgtttag aacccgtcag gtggtgaaga agtactgggc catcactgtg catgtcccca tgccctcagc aggagtcgtg gacatcccca ttgtggagaa ggaggcgcaa ggccagcagc aacaccacaa gatgacattg tccccgagct accgcatgga cgatgggaaa atggtgaaag tgcggcgcag ccggaatgcg caagttgctg taactcagta ccaggtgctc agcagcactc tctcctccgc cctcgtggag ctccagccca tcactggaat aaaacatcag cttcgagttc acttgtcttt tggattggat tgtccaatcc ttggtgatca caagtactca gactggaata ggttggcccc ccagaagctg tctgtgggca ccctgaagaa gctggggcta gaacagtcga aggcccgcta catccccctt cacctgcacg cccggcagct gatcctgcct gccctggggt ccgggaagga ggaactcaac ttggtctgca aacttcctcg cttctttgtg cattccctgc accgcctgcg tttagagatg ccaaatgagg atcaaaatga gaacaatgaa gccaagtgtc tgggagcaca Protein function: Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome (PubMed:27974379). Acts on position 39 in mitochondrial tRNA(Phe) (PubMed:28082677). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation (PubMed:27667664). [The UniProt Consortium]