RNF182 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 744 Sequence: atggccagtc aacctcctga agacactgcg gagtctcagg cctctgatga gctggagtgc aaaatctgtt acaatcgata caatctgaaa cagaggaaac ccaaagtgct ggagtgttgt catagggttt gtgccaaatg cctctacaag atcatagact ttggggactc cccacaaggt gtcattgtct gtcctttctg caggtttgag acgtgcctgc cagatgatga agttagtagc ctgcccgatg acaacaacat ccttgtaaac ttgacttgtg gaggcaaagg gaagaagtgc ctgccagaga accctactga gctgctgctc acccccaaga ggctggcctc tctggtcagt ccttctcaca cgtcctccaa ctgcctggtc ataaccatca tggaggtgca gagagagagc tccccgtccc tgagctccac tcctgtggta gaattttata ggcctgcgag tttcgactct gtcaccactg tgtcacacaa ctggactgtg tggaactgca cgtccctgct gtttcagaca tccatccggg tgttagtgtg gttgctaggt ttgctctact tcagctcctt acccttagga atctacttac tggtgtctaa gaaagtcacc cttggggtcg tctttgtcag cctggtccct tcgagcctcg ttattcttat ggtgtatggt ttttgccagt gtgtttgtca tgaatttcta gactgtatgg cacctccttc Protein function: E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843). Plays also a role in the inhibition of TLR- triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514). [The UniProt Consortium]