RHOQ (Vector pENTR223.1, Accession No. BC056154)

Length: 618 Sequence: ATGGCTCACG GGCCCGGCGC GCTGATGCTC AAGTGCGTGG TGGTCGGCGA CGGGGCGGTG GGCAAGACGT GCCTACTCAT GAGCTATGCC AACGACGCCT TCCCGGAGGA GTACGTGCCC ACCGTCTTCG ACCACTACGC AGTCAGCGTC ACCGTGGGGG GCAAGCAGTA CCTCCTAGGA CTCTATGACA CGGCCGGACA GGAAGACTAT GACCGTCTGA GGCCTTTATC TTACCCAATG ACCGATGTCT TCCTTATATG CTTCTCGGTG GTAAATCCAG CCTCATTTCA AAATGTGAAA GAGGAGTGGG TACCGGAACT TAAGGAATAC GCACCAAATG TACCCTTTTT ATTAATAGGA ACTCAGATTG ATCTCCGAGA TGACCCCAAA ACTTTAGCAA GACTGAATGA TATGAAAGAA AAACCTATAT GTGTGGAACA AGGACAGAAA CTAGCAAAAG AGATAGGAGC ATGCTGCTAT GTGGAATGTT CAGCTTTAAC CCAGAAGGGA TTGAAGACTG TTTTTGATGA GGCTATCATA GCCATTTTAA CTCCAAAGAA ACACACTGTA AAAAAAAGAA TAGGATCAAG ATGTATAAAC TGTTGTTTAA Protein function: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. [The UniProt Consortium]