RBM15B (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1692 Sequence: ATGCCCGAGG ATGACCAGCG GGCCACGCGC AACCTCTTCA TTGGTAACCT GGACCACAGC GTATCTGAGG TGGAGCTGCG AAGGGCCTTC GAGAAATATG GCATCATCGA GGAGGTGGTC ATCAAGAGGC CTGCCCGTGG CCAGGGCGGT GCCTATGCCT TCCTCAAGTT CCAGAACCTG GACATGGCCC ATAGGGCTAA GGTGGCCATG TCGGGCCGAG TGATTGGTCG CAACCCCATT AAGATAGGCT ATGGCAAGGC CAACCCCACC ACTCGTCTCT GGGTGGGTGG CCTGGGACCT AACACGTCAC TGGCGGCTCT GGCCCGAGAG TTTGACCGCT TTGGGAGCAT TCGGACCATT GATCACGTCA AAGGAGATAG CTTTGCCTAT ATTCAGTACG AGAGCTTGGA CGCAGCCCAG GCCGCCTGTG CTAAAATGAG GGGTTTTCCC TTGGGTGGAC CAGACCGCAG GCTCCGCGTG GATTTTGCCA AAGCAGAGGA GACTCGGTAC CCCCAGCAGT ACCAGCCCTC GCCACTCCCT GTGCATTATG AGCTGCTCAC AGATGGATAC ACCCGGCACC GCAACCTGGA CGCCGACCTG GTGCGGGACA GGACGCCCCC ACACCTTCTG TACTCAGACC GAGACCGGAC TTTTTTGGAA GGGGACTGGA CCAGCCCCAG TAAAAGCTCT GACCGCCGAA ACAGCCTTGA GGGCTACAGT CGCTCAGTGC GCAGCCGGAG TGGTGAGCGT TGGGGGGCAG ATGGAGACCG TGGTTTGCCC AAGCCCTGGG AAGAGAAGCG GAAACGGAGA AGCCTTTCCA GTGACCGTGG GAGGACAACC CATTCACCAT ATGAGGAACG GAGTAGGACC AAGGGCAGTG GGCAGCAGTC AGAGCGGGGC TCCGACCGCA CCCCTGAGCG CAGCCGCAAG GAGAACCACT CCAGTGAAGG GACCAAGGAG TCCAGCAGCA ACTCCCTCAG CAACAGCAGA CATGGGGCTG AGGAACGGGG CCACCACCAC CACCACCACG AGGCTGCAGA CTCTTCCCAC GGGAAGAAGG CAAGAGACAG CGAGCGCAAT CACCGGACCA CAGAGGCCGA GCCCAAGCCT CTGGAAGAGC CAAAACACGA GACCAAAAAG CTGAAGAATC TTTCAGAGTA CGCTCAGACA CTACAGCTGG GTTGGAATGG GCTTCTGGTG TTGAAAAACA GCTGCTTCCC CACGTCTATG CATATCCTAG AGGGGGACCA GGGGGTGATC AGCAGTCTCC TCAAAGACCA CACTTCTGGG AGCAAGCTGA CCCAGCTGAA GATCGCCCAG CGCCTTCGAC TGGACCAGCC CAAGCTTGAC GAGGTCACAC GACGCATCAA GCAGGGGAGC CCCAACGGCT ATGCGGTCCT CTTAGCCACC CAGGCAACCC CCAGTGGGCT TGGCACTGAG GGGATGCCCA CAGTAGAGCC CGGTCTGCAG AGGCGGCTTC TCAGGAACCT GGTCTCCTAC TTGAAACAGA AGCAGGCCGC AGGGGTGATC AGCTTGCCAG TGGGGGGGTC CAAGGGCAGA GACGGCACAG GCATGCTCTA CGCCTTCCCA CCCTGCGACT TTTCCCAGCA GTACCTCCAG TCAGCACTAA GGACATTGGG CAAGCTAGAA GAAGAACACA TGGTGATAGT CATCGTCAGA GACACTGCCT Protein function: RNA-binding protein that acts as a key regulator of N6- methyladenosine (m6A) methylation of RNAs, thereby regulating different processes, such as alternative splicing of mRNAs and X chromosome inactivation mediated by Xist RNA (PubMed:16129689, PubMed:27602518). Associated component of the WMM complex, a complex that mediates N6- methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:27602518). Plays a key role in m6A methylation, possibly by binding target RNAs and recruiting the WMM complex (PubMed:27602518). Involved in random X inactivation mediated by Xist RNA: acts by binding Xist RNA and recruiting the WMM complex, which mediates m6A methylation, leading to target YTHDC1 reader on Xist RNA and promoting transcription repression activity of Xist (PubMed:27602518). Functions in the regulation of alternative or illicit splicing, possibly by regulating m6A methylation (PubMed:16129689). Inhibits pre-mRNA splicing (PubMed:21044963). Also functions as a mRNA export factor by acting as a cofactor for the nuclear export receptor NXF1 (PubMed:19586903). [The UniProt Consortium]