RBM15B (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1257 Sequence: atgaggggtt ttcccttggg tggaccagac cgcaggctcc gcgtggattt tgccaaagca gaggagactc ggtaccccca gcagtaccag ccctcgccac tccctgtgca ttatgagctg ctcacagatg gatacacccg gcaccgcaac ctggacgccg acctggtgcg ggacaggacg cccccacacc ttctgtactc agaccgagac cggacttttt tggaagggga ctggaccagc cccagtaaaa gctctgaccg ccgaaacagc cttgagggct acagtcgctc agtgcgcagc cggagtggtg agcgttgggg ggcagatgga gaccgtggtt tgcccaagcc ctgggaagag aggcggaaac ggagaagcct ttccagtgac cgtgggagga caacccattc accatatgag gaacggagta ggaccaaggg cagtgggcag cagtcagagc ggggctccga ccgcacccct gagcgcagcc gcaaggagaa ccactccagt gaagggacca aggagtccag cagcaactcc ctcagcaaca gcagacatgg ggctgaggaa cggggccacc accaccacca ccacgaggct gcagactctt cccacgggaa gaaggcaaga gacagcgagc gcaatcaccg gaccacagag gccgagccca agcctctgga agagccaaaa cacgagacca aaaagctgaa gaatctttca gagtacgctc agacactaca gctgggttgg aatgggcttc tggtgttgaa aaacagctgc ttccccacgt ctatgcatat cctagagggg gaccaggggg tgatcagcag tctcctcaaa gaccacactt ctgggagcaa gctgacccag ctgaagatcg cccagcgcct tcgactggac cagcccaagc ttgacgaggt cacacgacgc atcaagcagg ggagccccaa cggctatgcg gtcctcttag ccacccaggc aacccccagt gggcttggca ctgaggggat gcccacagta gagcccggtc tgcagaggcg gcttctcagg aacctggtct cctacttgaa acagaagcag gccgcagggg tgatcagctt gccagtgggg gggtccaagg gcagagacgg cacaggcatg ctctacgcct tcccaccctg cgacttttcc cagcagtacc tccagtcagc actaaggaca ttgggcaagc tagaagaaga acacatggtg atagtcatcg tcagagacac Protein function: RNA-binding protein that acts as a key regulator of N6- methyladenosine (m6A) methylation of RNAs, thereby regulating different processes, such as alternative splicing of mRNAs and X chromosome inactivation mediated by Xist RNA (PubMed:16129689, PubMed:27602518). Associated component of the WMM complex, a complex that mediates N6- methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:27602518). Plays a key role in m6A methylation, possibly by binding target RNAs and recruiting the WMM complex (PubMed:27602518). Involved in random X inactivation mediated by Xist RNA: acts by binding Xist RNA and recruiting the WMM complex, which mediates m6A methylation, leading to target YTHDC1 reader on Xist RNA and promoting transcription repression activity of Xist (PubMed:27602518). Functions in the regulation of alternative or illicit splicing, possibly by regulating m6A methylation (PubMed:16129689). Inhibits pre-mRNA splicing (PubMed:21044963). Also functions as a mRNA export factor by acting as a cofactor for the nuclear export receptor NXF1 (PubMed:19586903). [The UniProt Consortium]