RAB7L1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 612 Sequence: atgggcagcc gcgaccacct gttcaaagtg ctggtggtgg gggacgccgc agtgggcaag acgtcgctgg tgcagcgata ttcccaggac agcttcagca aacactacaa gtccacggtg ggagtggatt ttgctctgaa ggttctccag tggtctgact acgagatagt gcggcttcag ctgtgggata ttgcagggca ggagcgcttc acctctatga cacgattgta ttatcgggat gcctctgcct gtgttattat gtttgacgtt accaatgcca ctaccttcag caacagccag aggtggaaac aggacctaga cagcaagctc acactaccca atggagagcc ggtgccctgc ctgctcttgg ccaacaagtg tgatctgtcc ccttgggcag tgagccggga ccagattgac cggttcagta aagagaacgg tttcacaggt tggacagaaa catcagtcaa ggagaacaaa aatattaatg aggctatgag agtcctcatt gaaaagatga tgagaaattc cacagaagat atcatgtctt tgtccaccca aggggactac atcaatctac aaaccaagtc ctccagctgg tcctgctgct Protein function: The small GTPases Rab are key regulators in vesicle trafficking (PubMed:24788816). Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner (PubMed:24788816). Recruits LRRK2 to the Golgi complex and stimulates LRRK2 kinase activity (PubMed:29212815). Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection (PubMed:22042847). [The UniProt Consortium]