PUS7 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 618 Sequence: atgaagaata tagtctctgc atttggcata atacccagaa ataatcgctt aatgtatatt catagctacc aaagctatgt gtggaataac atggtaagca agaggataga agactatgga ctaaaacctg ttccagggga cctcgttctc aaaggagcca cagccaccta tattgaggaa gatgatgtta ataattactc tatccatgat gtggtaatgc ccttgcctgg tttcgatgtt atctacccaa agcataaaat tcaagaagcc tacagggaaa tgctcacagc tgacaatctt gatattgaca acatgagaca caaaattcga gattattcct tgtcaggggc ctaccgaaag atcattattc gtcctcagaa tgttagctgg gaagtcgttg catatgatga tcccaaaatt ccacttttca acacagatgt ggacaaccta gaagggaaga caccaccagt ttttgcttct gaaggcaaat acagggctct gaaaatggat ttttctctac ccccttctac ttacgccacc atggccattc gagaagtgct aaaaatggat accagtatca agaaccagac gcagctgaat acaacctggc Protein function: Pseudouridylate synthase that catalyzes pseudouridylation of RNAs (PubMed:28073919, PubMed:29628141, PubMed:30778726). Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex (PubMed:29628141). Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3' (PubMed:28073919). In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types (PubMed:29628141). [The UniProt Consortium]