PTPN23 (Vector pUC, Accession No. BC004881)

Length: 1734 Sequence: atgggccccc aggcagcccc tcttaccatt cgagggccct cgtctgctgg ccagtccacc cctagtcccc acctggtgcc ttcacctgcc ccatctccag ggcctggtcc ggtaccccct cgccccccag cagcagaacc acccccttgc ctgcgccgag gcgccgcagc tgcagacctg ctctcctcca gcccggagag ccagcatggc ggcactcagt ctcctggggg tgggcagccc ctgctgcagc ccaccaaggt ggatgcagct gagggtcgtc ggccgcaggc cctgcggctg attgagcggg acccctatga acatcctgag aggctgcggc agttgcagca ggagctggag gcctttcggg gtcagctggg ggatgtggga gctctggaca ctgtctggcg agagctgcaa gatgcgcagg aacatgatgc ccgaggccgt tccatcgcca ttgcccgctg ctactcactg aagaaccggc accaggatgt catgccctat gacagtaacc gtgtggtgct gcgctcaggc aaggatgact acatcaatgc cagctgcgtg gaggggctct ccccatactg ccccccgcta gtggcaaccc aggccccact gcctggcaca gctgctgact tctggctcat ggtccatgag cagaaagtgt cagtcattgt catgctggtt tctgaggctg agatggagaa gcaaaaagtg gcacgctact tccccaccga gaggggccag cccatggtgc acggtgccct gagcctggca ttgagcagcg tccgcagcac cgaaacccat gtggagcgcg tgctgagcct gcagttccga gaccagagcc tcaagcgctc tcttgtgcac ctgcacttcc ccacttggcc tgagttaggc ctgcccgaca gccccagcaa cttgctgcgc ttcatccagg aggtgcacgc acattacctg catcagcggc cgctgcacac gcccatcatt gtgcactgca gctctggtgt gggccgcacg ggagcctttg cactgctcta tgcagctgtg caggaggtgg aggctgggaa cggaatccct gagctgcctc agctggtgcg gcgcatgcgg cagcagagaa agcacatgct gcaggagaag ctgcacctca ggttctgcta tgaggcagtg gtgagacacg tggagcaggt cctgcagcgc catggtgtgc ctcctccatg caaacccttg gccagtgcaa gcatcagcca gaagaaccac cttcctcagg actcccagga cctggtcctc ggtggggatg tgcccatcag ctccatccag gccaccattg ccaagctcag cattcggcct cctggggggt tggagtcccc ggttgccagc ttgccaggcc ctgcagagcc cccaggcctc ccgccagcca gcctcccaga gtctacccca atcccatctt cctccccacc ccccctttcc tccccactac ctgaggctcc ccagcctaag gaggagccgc cagtgcctga agcccccagc tcggggcccc cctcctcctc cctggaattg ctggcctcct tgaccccaga ggccttctcc ctggacagct ccctgcgggg caaacagcgg atgagcaagc ataactttct gcaggcccat aacgggcaag ggctgcgggc cacccggccc tctgacgacc ccctcagcct tctggatcca ctctggacac tcaacaagac Protein function: Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes (PubMed:18434552, PubMed:21757351). May act as a negative regulator of Ras-mediated mitogenic activity (PubMed:18434552). Plays a role in ciliogenesis (PubMed:20393563). [The UniProt Consortium]