PSMA8 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 729 Sequence: atggcgtctc gatatgacag ggcgatcact gtcttctccc cagacggaca cctttttcaa gttgaatatg cccaggaagc ggtgaagaaa ggatccaccg cggtcggaat tcgaggtacc aatatagttg ttcttggggt agaaaaaaaa tctgttgcca agcttcaaga tgaaagaact gtgaggaaaa tttgtgccct tgatgaccat gtctgcatgg cttttgcagt tttgacaatt tttataggac ttactgctga tgctagagta gtaataaaca gagcccgtgt ggagtgccag agccataagc ttacggttga ggacccagtc actgtagaat acataactcg cttcatagca actttaaagc agaaatatac ccaaagcaat ggacgaagac cttttggtat ttctgcctta attgtaggtt ttgatgatga tggtatctca agattgtatc agacagatcc ttctggtact tatcatgctt ggaaggcaaa tgcaataggc cgaagtgcta aaactgttcg agaatttcta gaaaagaatt acacagaaga tgccatagca agtgacagtg aagctatcaa gttagcaata aaagctttgc tagaagttgt ccagtctggt ggaagaaaca ttgaacttgc tataataaga agaaatcaac ctttgaagat gtttagtgca aaagaagttg aattatatgt aactgaaata Protein function: Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. The proteasome is a protein complexe that degrades unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Required for 20S core proteasome assembly, essential for the degradation of meiotic proteins RAD51 and RPA1 at late prophase I and the progression of meiosis I during spermatogenesis. Localizes to the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [The UniProt Consortium]