PSMA8 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 597 Sequence: atggcgtctc gatatgacag ggcgatcact gtcttctccc cagacggaca cctttttcaa gttgaatatg cccaggaagc ggtgaagaaa ggatccaccg cggtcggaat tcgaggactt actgctgatg ctagagtagt aataaacaga gcccgtgtgg agtgccagag ccataagctt acggttgagg acccagtcac tgtagaatac ataactcgct tcatagcaac tttaaagcag aaatataccc aaagcaatgg acgaagacct tttggtattt ctgccttaat tgtaggtttt gatgatgatg gtatctcaag attgtatcag acagatcctt ctggtactta tcatgcttgg aaggcaaatg caataggccg aagtgctaaa actgttcgag aatttctaga aaagaattac acagaagatg ccatagcaag tgacagtgaa gctatcaagt tagcaataaa agctttgcta gaagttgtcc agtctggtgg aagaaacatt gaacttgcta taataagaag aaatcaacct ttgaagatgt ttagtgcaaa agaagttgaa ttatatgtaa ctgaaataga Protein function: Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. The proteasome is a protein complexe that degrades unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Required for 20S core proteasome assembly, essential for the degradation of meiotic proteins RAD51 and RPA1 at late prophase I and the progression of meiosis I during spermatogenesis. Localizes to the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [The UniProt Consortium]