PRUNE (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 507 Sequence: atgctgagaa aagaccagaa gactatctat agacaaggcg tcaaggtggc cattagtgca atatatatgg atttggagat ctgtgaagtc ctggaacgct cccactctcc acccctgaag ctgacccctg cctcaagtac ccaccctaac ctccatgcct atcttcaagg caacacccag gtctctcgaa agaaacttct gcccctgctc caggaagccc tgtcagcata ttttgactcc atgaagatcc cttcaggaca gcctgagaca gcagatgtgt ccagggagca agtggacaag gaattggaca gggcaagtaa ctccctgatt tctggactga gtcaagatga ggaggaccct ccgctgcccc cgacgcccat gaacagcttg gtggatgagt gccctctaga tcaggggctg cctaaactct ctgctgaggc cgtcttcgag aagtgcagtc agatctcact gtcacagtct accacagcct ccctgtccaa Protein function: Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a negative regulator of NME1. Plays a role in the regulation of neurogenesis (PubMed:28334956). Involved in the regulation of microtubule polymerization (PubMed:28334956). [The UniProt Consortium]