PRICKLE3 (Vector pUC, Accession No. BC002468)

Length: 1848 Sequence: atgttcgcgc gtgggtcccg gaggcgccgc tccgggcgtg cgcctccaga ggcagaggac ccagaccggg gccagccctg caactcctgt agggagcagt gccctggctt cctgctccac ggctggagaa agatctgcca gcattgcaaa tgcccgcggg aggagcatgc agtgcacgcg gtgcctgtgg acctggaacg catcatgtgt cggctaatct cggacttcca gcgccactcc atctccgacg acgactcagg ctgtgcatcg gaggagtatg cctgggtgcc cccaggcctt aagccggagc aggtatatca atttttcagc tgcctcccag aggacaaggt cccctacgtc aacagtcctg gggagaaata caggatcaag cagctgctgc accagctgcc cccacacgac agtgaggcac agtactgcac agcactggaa gaggaggaaa agaaagagct ccgagccttt agccagcagc ggaagcggga gaatctgggg cgtggcatcg tgcgcatctt cccggtgacc atcactgggg ccatctgtga ggagtgcgga aagcagattg gaggtgggga catcgcagtg tttgccagcc gtgcaggcct gggtgcctgc tggcacccac agtgcttcgt gtgtaccacg tgccaggaac tgctggttga cctcatctac ttctaccatg ttggcaaggt ctactgcggg cgtcaccatg ccgaatgcct gcgtccacgc tgccaagcct gtgacgagat catcttctcc cctgagtgca cggaggctga gggccgccac tggcacatgg atcacttctg ctgctttgag tgtgaagctt cactaggagg gcagcgctat gtcatgcgtc agagccgccc ccactgctgc gcctgctacg aggcccgcca cgcggagtac tgtgatggct gtggggagca catcggcctg gaccaaggcc agatggctta cgagggccag cactggcatg cctcagaccg ctgcttctgc tgtagtcgct gtgggcgggc cctgctgggc cgcccattcc tgccacgccg aggcctaatc ttctgctctc gagcctgcag ccttgggtcc gagcccacag ctccagggcc gagccgccgc agctggagtg ccggccctgt cacagcccca cttgcagcct ccacagcctc tttctctgct gtgaaggggg catcagagac caccaccaaa ggcaccagca cagagttagc gccagctaca ggccctgagg agccctcccg ctttctgaga ggggctcccc accgccactc catgccggaa ctggggctcc gcagtgtccc cgagccgccc ccagagtccc ccggccagcc taacctgcgc ccagatgata gtgccttcgg tcgtcagagc accccacgcg tcagcttccg cgaccctctg gtgtctgaag gaggcccgcg ccggaccctg agtgcacccc cggcccagcg ccgcaggcca cgcagtcccc cacccagggc ccccagccgt cgccgccacc atcatcataa tcaccatcac catcacaacc gccacccaag cagacgtcgc cactatcaat gtgacgcggg atcagggtca gactcggaat cttgctccag ctcgccctcc agttccagtt ccgaatcatc agaggatgat ggcttcttcc taggagagcg catccctctg cccccgcatt tgtgcaggcc catgcctgct caggacactg caatggagac cttcaactcc ccatctttat cgctccccag ggactctcgc gcagggatgc ctcgtcaggc ccgagacaag aactgcatcg Protein function: Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation. PCP is maintained by two molecular modules, the global and the core modules, PRICKLE3 being part of the core module. Distinct complexes of the core module segregate to opposite sides of the cell, where they interact with the opposite complex in the neighboring cell at or near the adherents junctions. Involved in the organization of the basal body. Involved in cilia growth and positioning. [The UniProt Consortium]