PPP2R2A (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 1344 Sequence: atggcaggag ctggaggagg gaatgatatt cagtggtgtt tttctcaggt gaaaggagca gtagatgatg atgtagcaga agcagatata atttctacag tagaatttaa tcattctgga gaattactag caacaggaga taaaggtggt agagttgtca tctttcaaca ggagcaggag aacaaaatcc agtctcatag cagaggagaa tataatgttt acagcacctt ccagagccat gaaccagagt ttgactactt gaaaagttta gaaatagaag aaaagatcaa caaaattagg tggttacccc agaaaaatgc tgctcagttt ttattgtcta ccaatgataa aacaataaaa ttatggaaaa tcagtgaaag ggacaaaaga ccagaagggt ataacttgaa agaggaggat ggaaggtata gagatcctac tacagttact acactacgag tgccagtctt taggcctatg gatctaatgg ttgaggccag tccacgaaga atatttgcca atgctcatac atatcacatc aactcaattt ctattaatag tgattatgaa acatatttat ctgcagatga tttgcggatt aatctttggc atctggaaat tacagacagg agttttaaca ttgtggatat caagcctgcc aatatggaag agctaacaga ggtgattaca gcagcagaat ttcatccaaa cagctgtaac acatttgtat acagcagcag taaaggaact attcggctat gtgacatgag ggcatctgcc ctctgtgata gacattctaa attgtttgaa gaacctgaag atcccagtaa caggtcattt ttttccgaaa tcatctcctc tatttcggat gtaaaattca gccatagtgg tcgatatatg atgactagag actatttgtc agtcaaaatt tgggacttaa atatggaaaa caggcctgtg gaaacatacc aggtgcatga atacctcaga agtaaactct gttcactgta tgaaaatgac tgcatatttg acaaatttga atgttgttgg aatggatctg acagtgttgt catgactgga tcttacaata atttcttcag aatgtttgac agaaacacaa agcgagacat aaccctagaa gcatcgcggg aaaacaataa gcctcgcaca gttctgaagc ctcgcaaagt ctgtgcaagt ggcaagcgaa agaaagatga aataagtgtt gacagcctag acttcaataa gaaaatcctt cacacagcct ggcaccccaa ggaaaatatc attgccgtag ctactacaaa caatctgtat atatttcaag acaaagtgaa Protein function: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint (PubMed:33108758). [The UniProt Consortium]