POLA2 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1797 Sequence: atgtccgcat ccgcccagca gctggcggag gagctgcaga tcttcggcct agactgcgag gaggctctaa ttgagaaatt ggtagagctt tgtgttcagt atggacagaa tgaggaggga atggtaggcg agcttatagc cttctgcacc agcacacata aagttggcct tacctcagag atcctgaact cttttgagca tgagtttctg agcaaaagat tatcgaaagc caggcatagt acctgcaagg acagtggcca tgcaggagct agagacattg tttccattca agagctaatt gaagtggaag aagaagagga aatcctcttg aactcttaca ccacaccttc aaagggttct cagaagcgag ctatctctac cccagaaacc cccctaacaa aaaggagtgt gtcaactcgt agcccccatc agctactctc accgtcaagt ttctctccaa gtgctactcc ctcccagaaa tacaactcac gaagtaaccg aggagaagtg gttacctcct tcggcttagc acagggagta tcttggtctg ggagaggagg agctggaaac atcagcctga aggtcttggg atgtccagag gcactaactg ggagctacaa atccatgttt cagaagctcc cagacattcg agaagttctg acctgtaaga tagaagaact tggcagcgaa ctcaaggaac attacaagat tgaagctttc actcctttgc tagccccagc acaggagcct gtcactctgc tgggccagat tggctgtgat agcaacggga agctgaacaa caagtcagtg attctcgagg gagaccggga acattcctcg ggtgctcaaa ttccagtgga tttatctgag cttaaggaat attctctgtt tcctggacag gttgtaatta tggaaggaat caacaccact ggtaggaaac ttgttgccac caaactctac gagggtgtgc cacttccatt ttatcagccc actgaagagg atgcagactt tgagcaaagc atggtcctgg ttgcctgtgg accatacacc acatctgaca gcatcacgta tgaccccctg cttgacctga ttgctgtcat caaccatgac cggccagatg tctgcatcct gtttggccct ttcctggatg ctaagcatga acaggtggag aattgtctac tgacaagtcc atttgaagac attttcaagc agtgtctacg aacaattatt gaaggcacaa gaagctccgg ctcccacctt gtctttgtcc cgtcattgag agatgtgcac catgagcctg tgtaccccca gccgcctttc agctactccg atctgtctcg agaggacaaa aagcaagtac agtttgtgtc cgagccctgc agcctctcca taaacggagt gatcttcggc ttgacatcca cagatctgct tttccacctg ggggccgagg agatcagtag ttcttccgga acttcagaca gattcagccg aatactcaag cacatcttga cccagaggag ctactaccca ctctacccgc cccaagaaga catggccatt gactatgagt cgttctatgt ttacgcacag ctgcctgtca ccccagatgt cctcatcatc ccgtcagagc tgaggtactt cgtgaaggat gtcctcggct gtgtctgtgt gaaccctggg cgccttacca aagggcaggt gggaggcacc ttcgcccgac tctaccttag gaggccggca gcggacgggg cagagaggca gagcccatgc attgctgtgc aggtcgtcag Protein function: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis (PubMed:9705292). During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, an accessory subunit POLA2 and two primase subunits, the catalytic subunit PRIM1 and the regulatory subunit PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on the lagging and leading strand, respectively. [The UniProt Consortium]