PLEKHG2 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 2691 Sequence: atgttcccac agaacgctaa gcctggattc aagcacgctg gcagcgaagg ggaactctac cctccagaat ctcagccacc agtttcaggc tctgcacccc ctgaggacct ggaggatgct ggacccccaa cactggaccc ctctgggacc tcaatcactg aagaaatcct ggaactgctg aatcagcgag gccttcgaga tccagggccg tccacccatg acattcccaa gttccccgga gactcccagg tgcctggcga cagcgaaacc ctcacattcc aagccctgcc cagccgggac tcttcagaag aggaggagga ggaagaggaa gggctggaga tggatgaacg ggggccttcc ccactccacg tcctggaagg gctcgaaagt tccattgcag ctgaaatgcc cagcattccc tgccttacca aaattcctga cgtgcccaac cttcctgaaa ttcccagcca ctgtgaaatt cccgaaggtt ctcgccttcc tagtctctct gacatttccg atgtttttga gatgccctgc cttccagcca tacctagtgt ccccaacacc cccagtctgt ctagcactcc caccctctcc tgtgactcct ggctccaagg gcctctgcag gaaccagctg aggctccagc caccaggaga gaactgtttt ctgggagcaa tcctgggaaa ctgggagagc cgccttcagg aggcaaggca gggccagagg aggatgaaga aggggtatca ttcacagact tccagcccca ggatgtcacc caacatcagg gattcccaga tgagctggca ttccgctctt gctcagaaat ccggagcgcc tggcaggcat tggaacaggg acagctggcc cggccaggct tcccagagcc actgctgatc ctggaggatt cggatctggg tggagacagc gggagcggga aggcaggagc cccgagttca gaaaggacgg cgtcccgagt gcgagagctg gcccggcttt acagcgagcg gatccagcag atgcagcggg cggagactcg ggcatcagcc aatgccccgc gccgccggcc tcgggttctg gcccaacccc agccatcccc ctgtctgccc caggagcagg cagagccagg gctcctgcct gcctttggac acgtgctggt atgtgagctg gccttcccac tgacatgtgc ccaggagtct gtccccctgg gtcctgctgt ctgggttcaa gctgccatac ctttgtcaaa gcagggaggc agcccggatg gccagggtct acatgtttcc aatttgccta agcaagacct tccgggcatc cacgtttcag ctgctaccct tttgcctgag caaggaggtt cccggcatgt ccaggctcca gccgccacac ctttgcccaa gcaagaaggc cccctgcacc tccaggtgcc ggctcttaca actttctctg atcaaggcca cccagaaatc caagttccag ccaccactcc tttgcctgag cataaaagtc acatggttat accagctcca tccaccgcct tttgtcctga gcagggacac tgtgcggaca tccacgttcc caccactcca gctttgccca aggagatttg ttctgatttc acagtttcag tcaccacccc tgtgcccaag caagaaggtc acctagacag cgagagccca accaatatcc cactgacaaa gcaaggaggt tccagggatg ttcagggccc agaccctgtc tgcagtcaac ccatccagcc tttgtcttgg catggaagca gcctggatcc ccagggccca ggcgacaccc taccaccctt gccatgtcac ctcccagacc ttcagattcc aggtacctca cctttgcctg cacatggaag ccacctggac catcggatcc cagccaacgc cccactgtct ttgtcccagg agctcccaga cactcaggtt ccagctacca cacctttgcc cctgccacaa gtcctcacag acatctgggt ccaagccctc ccaacttcac ccaagcaggg aagcctccca gacatccagg gtccagcggc tgcacctcca cttccggagc caagccttac agatacacag gtccaaaaac tcacaccttc gttggagcag aagagcctca tagatgccca tgttccagct gccacacctt tacctgagag aggaggctct ctagacattc agggcctctc acccacccca gttcagacca ccatggtttt gtccaaacca ggaggctcct tagcctctca cgttgccagg ttggagtctt cagacttgac gccacctcat agtcccccac cttccagccg tcagctcctg ggccccaatg cagctgccct ctccagatac ctggcagcct catatatcag ccaaagcctg gctcggcggc aggggcctgg gggaggggcc cccgcagcct cccggggctc ctggtcctct gctcccacgt cacgggcatc ttcgccgccc ccccagcccc agccaccacc tcccgcagcc aggcggctca gctatgccac gacggttaac atccacgtgg gcgggggtgg gcggctgcgg ccagccaagg cccaggtccg gttgaaccac cctgctctct tggcctccac acaggaatct atgggccttc acagggccca gggggctcct gatgccccct tccacatgtg Protein function: May be a transforming oncogene with exchange activity for CDC42. May be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42. Activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein) (PubMed:18045877). Involved in the regulation of actin polymerization (PubMed:26573021). [The UniProt Consortium]