PCDH8 (Vector pUC, Accession No. BC036025)

Length: 3213 Sequence: atgagtcctg tgaggcgttg gggcagcccc tgccttttcc ccttgcagct cttcagcctc tgctgggtgc tctcagtggc ccagagcaaa acagtccgat acagcacctt cgaggaggat gcccccggca cggtcatcgg gaccctggcc gaggacctgc acatgaaagt atcgggtgac acaagcttcc gcctgatgaa gcaattcaac agctctctgc tccgggtgcg cgaaggcgac gggcagctga ccgtcgggga cgccggcctg gaccgcgagc ggctgtgtgg ccaggccccg cagtgcgtgc tggccttcga tgtggtcagc ttctcgcagg agcagttccg gctggtgcac gtggaggtag aggtgaggga cgtcaacgac cacgcgccgc gcttccccag ggcccagatc ccggtagagg tgtccgaggg tgcggcagtg ggcacgcgca tccccttgga ggtgccggtg gacgaggacg tgggcgccaa cgggctgcag accgtgcgcc tggccgagcc gcacagcccc tttcgcgtgg agctgcagac gcgagcggac ggcgctcagt gcgcagacct ggtgctgctg caggagctgg accgcgagag ccaggccgcc tacagcctgg agctggtggc ccaggacggc ggccgcccgc cgcgctccgc cacggctgcc ctcagcgtgc gcgtcctgga tgcgaatgac cacagcccgg ccttcccgca gggcgccgtg gccgaagtgg agctggcgga agacgcgccc gtgggctccc tgcttctcga cctggacgca gccgaccccg acgagggacc taacggcgac gtggtgttcg catttggcgc ccgcaccccg ccggaggcgc gccgcctctt tcggcttgac ccgcgatcag gccgcctcac cctggccggg cccgtggact acgagcgtca ggacacctac gagctggacg tgcgggcgca ggaccgcgga cccgggcccc gcgctgccac ctgcaaggtc atcgtgcgca tccgagacgt caatgacaac gcacccgaca tcgccatcac cccgctggcc gccccaggcg cgccggcaac ctcacccttc gccgctgccg ccgccgccgc tgcactcggg ggagcggacg ctagctcgcc ggcgggagcc gggacgccgg aggctggtgc cacttcgctg gtgccggagg gggcggcgcg cgagagcctg gtggccctgg tcagcacctc ggacagggac tcgggcgcca acgggcaagt gcgctgcgcc ctctatgggc acgagcactt ccggctgcag ccggcctacg cgggcagcta cctggtggtg accgcggcgt cgctggaccg cgaacgcatc gccgagtaca acttgacgct ggtggccgag gatcgcggcg cgcccccgct gcgcacagtg cggccctaca cggtgcgtgt gggcgacgag aacgacaacg cgccgctctt cacgcggccg gtctatgagg tgtcggtgcg cgagaacaac ccgccaggcg cctacctggc cacggtggcc gcccgcgacc gggacctggg ccgcaacggc caggtcacct accggctgct ggaggccgag gtgggccgcg ccgggggcgc cgtgtccact tatgtctcgg tggacccagc taccggagcc atctacgcgc tgcgcagctt cgactatgag acgctgcgcc aactcgacgt tcgcatccaa gctagcgacg gcggctcccc tcagctttcc agcagcgccc tagtgcaagt gcgcgtgctg gaccagaacg accatgcgcc agtcctggtg cacccggcgc cagccaatgg ctccctagaa gtggcggtgc ctgggcgcac cgcaaaggac acggttgtgg cccgtgtgca ggcccgggat gcagacgagg gagccaacgg ggagctggcg ttcgagctgc agcagcagga gccgcgcgaa gccttcgcca tcggccgccg cacgggggag atactgctca ccggcgacct ctcgcaggag ccacccggtc gcgtgttcag ggcgctcctg gtcatatccg acggcggccg tcccccgctc accaccaccg caactgtcag cttcgtggta acagcagggg gcgggcgtgg gccggctgcg cctgccagtg caggaagccc ggagcgttcc cgcccgcctg gctctcggct cggggtgtcc gggtcggtgc tgcaatggga cacgccgctg atcgtcatca tcgtgctggc cgggagctgc acgctgctgc tggccgccat catcgccatc gccaccacct gcaaccgccg caagaaggag gtgcgcaaag ggggggccct ccgggaagag cggcccgggg cggcgggcgg cggagcctcg gctcccggct ccccggagga ggccgcccgg ggagccgggc ccaggcccaa catgttcgac gtgctcacct tccctggcac cggcaaagcg ccctttggct gccccgcggc ggacgcgcct ccgcctgcgg tcgccgcggc cgaagtgccg ggctcagagg gcggcagcgc cactggggaa agcgcctgtc acttcgaggg gcagcagcgg ctccgcggcg cgcacgccga gccctacggt gcctccccgg gttttggaaa ggagccggcg ccccctgtgg cggtgtggaa aggacactcc ttcaacacca tttctggcag agaagcagag aagttcagcg gcaaagacag cggtaaaggg gacagtgatt tcaacgacag cgattccgac atcagcgggg acgctctgaa aaaggatctc atcaaccaca tgcagagtgg actgtgggcg tgcaccgctg agtgtaagat cctgggccac tctgaccgct gctggagccc atcctgcagc gggcccaacg cacatccatc gcctcaccca ccagcccaga tgtcaacctt ctgtaagagc acgtcactgc ctcgggatcc tctgcgcagg gacaattact accaggccca gctgcccaag acagtggggc tgcagagcgt ctatgagaaa gtactgcaca gagactatga caggacagtc actctgctct cccctccccg tccagggagg ctcccagacc tgcaggagat tggagtaccc ctctaccagt cccctcctgg caggtacctg tccccgaaga agggagccaa tgaaaatgtg Protein function: Calcium-dependent cell-adhesion protein. May play a role in activity-induced synaptic reorganization underlying long term memory. Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis. [The UniProt Consortium]