PARVB (Vector pUC, Accession No. BC046103)

Length: 1053 Sequence: atgaagaagg acgagtcgtt cctgggcaag ctgggcggca ccctggccag gaagcggagg gcgcgcgagg tgagtgacct gcaggaagaa ggcaagaatg ccatcaactc accgatgtcc cccgccctgg cggatgttca ccctgaagac acccagctcg aggagaacga ggagcgcacg atgattgacc ccacttccaa ggaagacccc aagttcaagg aactggtcaa ggtcctcctc gactggatta atgacgtgct ggtggaggag aggatcattg tgaagcagct ggaggaagac ctgtatgacg gccaggtgct gcagaagctc ttggaaaaac tggcagggtg caagctgaat gtggctgagg tgacacagtc cgaaataggg cagaaacaga agctgcagac ggtgctggaa gcagtacatg acctgctgcg gccccgaggc tgggcgctcc ggtggagcgt ggactcaatt cacgggaaga acctggtggc catcctccac ctgctggtct ctctggccat gcacttcagg gcccccatcc gccttcctga gcatgtaacg gtgcaggtgg tggtcgtgcg gaaacgggaa ggcctgctgc attccagcca catctcggag gagctgacca caactacaga gatgatgatg ggccggttcg agcgggatgc cttcgacacg ctgttcgacc acgccccgga taagctcagc gtggtgaaga agtctctcat cacttttgtg aacaagcacc tgaacaagct gaatttggag gtgacggaac tggagaccca gtttgcagat ggcgtgtacc tggttctgct catgggcctt ctggaagact actttgttcc tctccaccac ttctacctga ctccggaaag cttcgatcag aaggtccaca atgtgtcctt tgcctttgag ctgatgctgg acggaggcct caagaaaccc aaggctcgtc ctgaagacgt ggttaacttg gacctcaaat ccaccctgag ggttctttac aacctgttca ccaagtacaa gaacgtggag Protein function: Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration. [The UniProt Consortium]