PAPSS2 (Vector pUC, Accession No. BC009894)

Length: 1845 Sequence: atgtcgggga tcaagaagca aaagacggag aaccagcaga aatccaccaa tgtagtctat caggcccacc atgtgagcag gaataagaga gggcaagtgg ttggaacaag gggtgggttc cgaggatgta ccgtgtggct aacaggtctc tctggtgctg gaaaaacaac gataagtttt gccctggagg agtaccttgt ctcccatgcc atcccttgtt actccctgga tggggacaat gtccgtcatg gccttaacag aaatctcgga ttctctcctg gggacagaga ggaaaatatc cgccggattg ctgaggtggc taagctgttt gctgatgctg gtctggtctg cattaccagc tttatttctc cattcgcaaa ggatcgtgag aatgcccgca aaatacatga atcagcaggg ctgccattct ttgaaatatt tgtagatgca cctctaaata tttgtgaaag cagagacgta aaaggcctct ataaaagggc cagagctggg gagattaaag gatttacagg tattgattct gattatgaga aacctgaaac tcctgagcgt gtgcttaaaa ccaatttgtc cacagtgagt gactgtgtcc accaggtagt ggaacttctg caagagcaga acattgtacc ctatactata atcaaagata tccacgaact ctttgtgccg gaaaacaaac ttgaccacgt ccgagctgag gctgaaactc tcccttcatt atcaattact aagctggatc tccagtgggt ccaggttttg agcgaaggct gggccactcc cctcaaaggt ttcatgcggg agaaggagta cttacaggtt atgcactttg acaccctgct agatgatggc gtgatcaaca tgagcatccc cattgtactg cccgtctctg cagaggataa gacacggctg gaagggtgca gcaagtttgt cctggcacat ggtggacgga gggtagctat cttacgagac gctgaattct atgaacacag aaaagaggaa cgctgttccc gtgtttgggg gacaacatgt acaaaacacc cccatatcaa aatggtgatg gaaagtgggg actggctggt tggtggagac cttcaggtgc tggagaaaat aagatggaat gatgggctgg accaataccg tctgacacct ctggagctca aacagaaatg taaagaaatg aatgctgatg cggtgtttgc attccagttg cgcaatcctg tccacaatgg ccatgccctg ttgatgcagg acactcgccg caggctccta gagaggggct acaagcaccc ggtcctccta ctacaccctc tgggcggctg gaccaaggat gacgatgtgc ctctagactg gcggatgaag cagcacgcgg ctgtgctcga ggaaggggtc ctggatccca agtcaaccat tgttgccatc tttccgtctc ccatgttata tgctggcccc acagaggtcc agtggcactg caggtcccgg atgattgcgg gtgccaattt ctacattgtg gggagggacc ctgcaggaat gccccatcct gaaaccaaga aggatctgta tgaacccact catgggggca aggtcttgag catggcccct ggcctcacct ctgtggaaat cattccattc cgagtggctg cctacaacaa agccaaaaaa gccatggact tctatgatcc agcaaggcac aatgagtttg acttcatctc aggaactcga atgaggaagc tcgcccggga aggagagaat cccccagatg gcttcatggc ccccaaagca tggaaggtcc tgacagatta ttacaggtcc ctggagaaga Protein function: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate, APS appears to be only an intermediate in the sulfate-activation pathway. May have an important role in skeletogenesis during postnatal growth. [The UniProt Consortium]