PAPSS1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1875 Sequence: atggagatcc ccgggagcct gtgcaagaaa gtcaagctga gcaataacgc gcagaactgg ggaatgcaga gagcaaccaa tgtcacctac caagcccatc atgtcagcag gaacaagaga ggtcaggtgg tggggaccag aggtggcttt cgtggttgca cagtttggct aacaggcttg tctggagcgg gaaagactac tgtgagcatg gccttggagg agtacctggt ttgtcatggt attccatgct acactctgga tggtgacaat attcgtcaag gtctcaataa aaatcttggc tttagtcctg aagacagaga agagaatgtt cgacgcatcg cagaagttgc taaactgttt gcagatgctg gcttagtgtg catcacaagt ttcatatcac cttacactca ggatcgcaac aatgcaaggc aaattcatga aggtgcaagt ttaccgtttt ttgaagtatt tgttgatgct cctctgcatg tttgtgaaca gagggatgtc aaaggactct acaaaaaagc ccgggcagga gaaattaaag gtttcactgg gatcgattct gaatatgaaa agccagaggc ccctgagttg gtgctgaaaa cagactcctg tgatgtaaat gactgtgtcc agcaagttgt ggaacttcta caggaacggg atattgtacc tgtggatgca tcttatgaag taaaagaact atatgtgcca gaaaataaac ttcatttggc aaaaacagat gcggaaacat taccagcact gaaaattaat aaagtggata tgcagtgggt gcaggttttg gcagaaggtt gggcaacccc attgaatggc tttatgagag agagggagta cttgcagtgc cttcattttg attgtcttct ggatggaggt gtcattaact tgtcagtacc tatagttctg actgcgactc atgaagataa agagaggctg gacggctgta cagcatttgc tctgatgtat gagggccgcc gtgtggccat tcttcgcaat ccagagtttt ttgagcacag gaaagaggag cgctgtgcca gacagtgggg aacgacatgc aagaaccacc cctatattaa gatggtgatg gaacaaggag attggctgat tggaggagat cttcaagtct tggatcgagt ttattggaat gatggtcttg atcagtatcg tcttactcct actgagctaa agcagaaatt taaagatatg aatgctgatg ctgtctttgc atttcaacta cgcaacccag tgcacaatgg acatgccctg ttaatgcagg atacccataa gcaacttcta gagaggggct accggcgccc tgtcctcctc ctccaccctc tgggtggctg gacaaaggat gacgatgttc ctttgatgtg gcgtatgaag cagcatgctg cagtgttgga ggaaggagtt ctgaatcctg agacgacagt ggtggccatc ttcccatctc ccatgatgta tgctggacca actgaggtcc agtggcattg cagagcacgg atggttgcag gagccaactt ttacattgtt ggacgagacc ctgctggcat gcctcatcca gaaacaggga aggatcttta tgagccaagt catggtgcca aagtgctgac gatggcccct ggtttaatca ctttggaaat agttcccttt cgagttgcag cttacaacaa gaaaaagaag cgtatggact actatgactc tgaacaccat gaagactttg aatttatttc aggaacacga atgcgcaaac ttgctcgaga aggccagaaa ccacctgaag gtttcatggc tcccaaggct tggaccgtgc tgacagaata ctacaaatcc ttggagaaag Protein function: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate, APS appears to be only an intermediate in the sulfate-activation pathway (PubMed:9576487, PubMed:9668121, PubMed:9648242, PubMed:14747722). Required for normal biosynthesis of sulfated L-selectin ligands in endothelial cells (PubMed:9576487). [The UniProt Consortium]