PACS2 (Vector pUC, Accession No. BC065220)

Length: 2670 Sequence: ATGGCCGAGC GAGGCCGCCT CGGCCTCCCC GGCGCGCCCG GCGCGCTCAA CACGCCCGTG CCCATGAACC TGTTCGCCAC CTGGGAGGTG GACGGCTCCA GCCCCAGCTG CGTGCCCAGG TTGTGCAGCC TGACTCTGAA GAAGCTGGTG GTCTTCAAGG AGCTGGAGAA GGAGCTGATC TCCGTGGTGA TCGCTGTCAA GATGCAGGGC TCCAAACGAA TCCTGCGGTC CCATGAGATT GTGCTGCCCC CCAGTGGACA AGTGGAGACA GACCTGGCCC TGACCTTCTC CTTGCAGTAT CCTCACTTCT TGAAGAGGGA AGGCAACAAG CTTCAGATCA TGCTGCAGCG CAGAAAGCGC TACAAGAACA GAACCATCCT GGGCTACAAG ACGCTGGCCG CGGGCTCCAT CAGCATGGCT GAGGTGATGC AACACCCGTC TGAAGGTGGC CAGGTGCTGA GCCTCTGCAG CAGCATCAAG GAGGCCCCCG TCAAGGCGGC CGAGATCTGG ATCGCCTCCC TGTCCAGCCA GCCCATTGAC CACGAAGACA GCACCATGCA GGCCGGCCCC AAGGCCAAGT CCACGGATAA CTACTCCGAG GAGGAGTATG AGAGCTTCTC CTCCGAGCAG GAGGCCAGTG ACGACGCCGT GCAGGGGCAG GACTTGGACG AGGACGACTT TGACGTGGGG AAGCCGAAGA AGCAGCGGAG ATCGATTGTA AGAACGACGT CCATGACCAG GCAACAGAAC TTCAAGCAGA AAGTGGTAGC GCTGCTGCGG AGGTTCAAAG TGTCCGACGA GGTCCTGGAC TCGGAGCAGG ACCCTGCGGA GCACATCCCC GAGGCAGAGG AGGACCTGGA CCTCCTGTAT GACACCCTGG ACATGGAGCA CCCCAGCGAC AGCGGCCCCG ACATGGAGGA TGACGACAGC GTCCTCAGCA CCCCCAAGCC GAAGCTGCGG CCATACTTTG AAGGCCTGTC GCACTCGAGC TCGCAGACGG AGATTGGGAG CATCCACAGC GCCCGCAGCC ACAAGGAGCC CCCAAGCCCG GCTGACGTGC CCGAGAAGAC GCGGTCCCTG GGAGGCAGGC AGCCGAGCGA CAGTGTCTCT GACACGGTGG CCCTCGGTGT GCCAGGCCCG AGGGAGCACC CTGGACAGCC TGAGGACAGC CCCGAGGCTG AGGCCTCCAC CCTGGATGTG TTCACGGAGA GGCTGCCGCC CAGCGGGAGG ATCACCAAGA CAGAGTCCCT TGTCATCCCC TCCACCAGGT CCGAGGGGAA GCAGGCTGGC CGACGGGGCC GGAGCACATC CTTGAAGGAG CGGCAGGCAG CACGGCCCCA GAATGAGCGG GCCAACAGCC TGGACAACGA GCGCTGCCCG GACGCCCGGA GCCAGCTACA GATCCCCAGG AAGACTGTGT ATGACCAGCT CAACCACATC CTCATCTCCG ATGACCAGCT TCCCGAAAAC ATCATCCTTG TCAACACCTC GGACTGGCAG GGGCAGTTCC TCTCCGACGT CCTGCAGAGG CACACGCTCC CCGTGGTGTG CACGTGCTCT CCTGCGGACG TCCAGGCGGC CTTCAGCACC ATCGTCTCAC GGATACAGAG ATACTGCAAC TGCAATTCCC AGCCCCCGAC CCCCGTGAAG ATCGCCGTGG CGGGAGCGCA GCATTACCTC AGTGCCATCC TGCGGCTCTT TGTGGAGCAG CTGTCCCACA AGACACCCGA CTGGCTCGGC TACATGCGCT TCCTGGTCAT CCCACTGGGC TCCCACCCCG TGGCCAGGTA CCTAGGCTCC GTGGACTACC GCTACAACAA CTTCTTCCAG GACCTGGCCT GGAGAGACCT GTTCAACAAG CTGGAGGCCC AGAGTGCGGT ACAGGACACG CCAGACATTG TGTCACGCAT CACGCAGTAC ATCGCAGGGG CCAACTGTGC CCACCAGCTC CCCATCGCAG AGGCCATGCT GACCTACAAG CAGAAGAGCC CTGACGAAGA GTCCTCCCAA AAGTTCATTC CCTTTGTCGG GGTTGTGAAG GTTGGAATTG TGGAGCCATC CTCGGCCACA TCAGGCGACT CGGACGACGC GGCCCCCTCG GGCTCTGGCA CGCTCTCCTC CACCCCGCCG TCCGCATCTC CTGCGGCCAA GGAGGCCTCA CCCACCCCGC CCTCCTCCCC GTCGGTGAGC GGAGGCCTGT CCTCCCCCAG CCAGGGTGTC GGCGCCGAGC TGATGGGGCT GCAGGTGGAC TACTGGACGG CAGCACAGCC TGCGGACAGG AAGAGGGACG CCGAGAAGAA GGACCTGCCT GTCACCAAAA ACACGCTCAA GTGCACTTTC CGGTCCCTCC AGGTCAGCAG GCTGCCCAGC AGCGGCGAGG CTGCAGCCAC GCCCACCATG TCCATGACCG TGGTCACCAA GGAGAAGAAC AAGAAGGTGA TGTTTCTGCC CAAGAAAGCG AAGGACAAGG ACGTGGAGTC TAAGAGCCAG TGCATTGAGG GCATCAGCCG GCTCATCTGC ACTGCCAGGC AGCAGCAGAA CATGCTGCGG GTCCTCATCG ACGGCGTGGA GTGCAGCGAC GTCAAGTTCT TCCAGCTGGC CGCGCAGTGG TCCTCGCACG TGAAGCACTT CCCCATCTGC ATCTTCGGAC ACTCCAAGGC Protein function: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. [The UniProt Consortium]