OSBPL10 (Vector pUC, Accession No. BC003168)

Length: 2295 Sequence: atggagaggg cagtccaggg cacagacggc ggcgggggta gcaacagcag cagccgcagc agcagccgtg ctacctcggc gggctcctcg ccctcctgct ctctggcggg ccggggggtc tccagccggt cggcggcggc cgggctcggc ggcgggggaa gccgcagcag cccgggctct gtggccgcta gcccgtccgg gggaggcggc cgcaggaggg agccggcgct cgagggcgtg ctcagcaaat acaccaacct cctccagggc tggcagaaca ggtacttcgt actggatttc gaggctggca tcctgcagta ttttgtgaat gagcaaagca aacaccagaa gcctcgagga gtcctgtctt tatctggagc catagtgtcc ctgagcgatg aagctcccca catgctggtg gtgtactctg ctaatggaga gatgtttaaa ctgagagctg ctgatgcaaa agagaaacaa ttctgggtga ctcagcttcg agcttgtgcc aaataccaca tggaaatgaa ttctaagagt gctccaagct cccgaagccg aagtctcact ttgctcccac atggaacacc caattctgcg tctccctgta gccagagaca cctcagtgtg ggggcccccg gtgttgtcac aatcacgcat cacaagtcgc ctgcagccgc ccgaagagcc aagagtcagt attccggcca gcttcacgaa gtcagagaga tgatgaacca ggtggaaggg cagcagaaga accttgtgca cgccattgag tccctgccag ggtccggccc cctcactgcc ttggaccagg acctgctgct cctgaaagct acctctgctg ccaccctcag ctgccttggg gagtgcctca acttgttaca gcagagtgtg caccaggcgg gccagcccag ccagaagcca ggagcctcgg aaaacatcct gggatggcac gggtccaagt cacattccac agagcagctg aaaaatggga cacttggctc tttgccatca gccagtgcca acataacctg ggcaatttta ccaaactctg ctgaagacga acaaacctca cagccagagc cagagccaaa ctcaggctct gaattggttt tgtctgaaga tgaaaaaagt gacaatgaag ataaggaaga gacggaattg ggcgtcatgg aggatcagcg tagtataatt cttcatctca tttcacaact caaacttgga atggatttga ccaaggtggt gcttcccacc tttatcctgg agaagcgatc tttgctggag atgtatgcag atttcatggc gcacccagac ctactgctgg ccatcaccgc tggggccaca ccagaggaga gagtcatttg cttcgttgag tattatctca cagcctttca cgagggccgc aagggcgctt tagccaagaa gccctacaac cccatcatag gcgagacatt tcactgctcc tgggaagttc ccaaggacag ggtcaagcct aagaggactg cttcccgctc tcctgccagc tgtcacgaac acccaatggc cgatgaccct tccaaaagct acaaactaag gtttgtggct gagcaagtgt cccatcaccc acccatctcc tgcttctact gtgagtgcga ggagaagaga ctgtgtgtca acactcatgt atggaccaaa agcaagttca tgggcatgtc cgtgggggtc tctatgatag gggaaggtgt gttgaggctc ctggaacacg gggaggagta cgtattcacc ctgcctagtg cctacgcccg gtccattctc accatcccat gggtggagct cggaggaaaa gtcagcatca actgtgccaa gactgggtac tcagcgacag tgatattcca cacgaagcct ttctatggag ggaaagtcca cagggttacc gcagaagtga agcacaaccc aaccaacacc attgtttgta aagcccatgg ggaatggaat ggtactttag agttcaccta caacaatgga gaaaccaaag tcatcgacac aaccacactg ccagtgtatc ccaagaagat cagacctctt gagaagcagg gacccatgga gtccaggaac ctctggcggg aggtgacccg atacctgcgg ctgggggaca ttgacgcagc caccgagcag aagcggcacc tagaggagaa gcaacgggtg gaggaacgga agcgcgagaa cctccgcaca ccatggaagc ccaaatattt tatccaggag ggcgatggct gggtatactt caatcccctc tggaaagcac Protein function: Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (PubMed:23934110) (Probable). Plays a role in negative regulation of lipid biosynthesis (PubMed:19554302). Negatively regulates APOB secretion from hepatocytes (PubMed:19554302, PubMed:22906437). Binds cholesterol and acidic phospholipids (PubMed:22906437). Also binds 25- hydroxycholesterol (PubMed:17428193). Binds phosphatidylserine (PubMed:23934110). [The UniProt Consortium]