NUAK2 (Vector pUC, Accession No. BC017306)

Length: 1887 Sequence: atggagtcgc tggttttcgc gcggcgctcc ggccccactc cctcggccgc agagctagcc cggccgctgg cggaagggct gatcaagtcg cccaagcccc taatgaagaa gcaggcggtg aagcggcacc accacaagca caacctgcgg caccgctacg agttcctgga gaccctgggc aaaggcacct acgggaaggt gaagaaggcg cgggagagct cggggcgcct ggtggccatc aagtcaatcc ggaaggacaa aatcaaagat gagcaagatc tgatgcacat acggagggag attgagatca tgtcatcact caaccaccct cacatcattg ccatccatga agtgtttgag aacagcagca agatcgtgat cgtcatggag tatgccagcc ggggcgacct ttatgactac atcagcgagc ggcagcagct cagtgagcgc gaagctaggc atttcttccg gcagatcgtc tctgccgtgc actattgcca tcagaacaga gttgtccacc gagatctcaa gctggagaac atcctcttgg atgccaatgg gaatatcaag attgctgact tcggcctctc caacctctac catcaaggca agttcctgca gacattctgt gggagccccc tctatgcctc gccagagatt gtcaatggga agccctacac aggcccagag gtggacagct ggtccctggg tgttctcctc tacatcctgg tgcatggcac catgcccttt gatgggcatg accataagat cctagtgaaa cagatcagca acggggccta ccgggagcca cctaaaccct ctgatgcctg tggcctgatc cggtggctgt tgatggtgaa ccccacccgc cgggccaccc tggaggatgt ggccagtcac tggtgggtca actggggcta cgccacccga gtgggagagc aggaggctcc gcatgagggt gggcaccctg gcagtgactc tgcccgcgcc tccatggctg actggctccg gcgttcctcc cgccccctcc tggagaatgg ggccaaggtg tgcagcttct tcaagcagca tgcacctggt gggggaagca ccacccctgg cctggagcgc cagcattcgc tcaagaagtc ccgcaaggag aatgacatgg cccagtctct ccacagtgac acggctgatg acactgccca tcgccctggc aagagcaacc tcaagctgcc aaagggcatt ctcaagaaga aggtgtcagc ctctgcagaa ggggtacagg aggaccctcc ggagctcagc ccaatccctg cgagcccagg gcaggctgcc cccctgctcc ccaagaaggg cattctcaag aagccccgac agcgcgagtc tggctactac tcctctcccg agcccagtga atctggggag ctcttggacg caggcgacgt gtttgtgagt ggggatccca aggagcagaa gcctccgcaa gcttcagggc tgctcctcca tcgcaaaggc atcctcaaac tcaatggcaa gttctcccag acagccttgg agctcgcggc ccccaccacc ttcggctccc tggatgaact cgccccacct cgccccctgg cccgggccag ccgaccctca ggggctgtga gcgaggacag catcctgtcc tctgagtcct ttgaccagct ggacttgcct gaacggctcc cagagccccc actgcggggc tgtgtgtctg tggacaacct cacggggctt gaggagcccc cctcagaggg ccctggaagc tgcctgaggc gctggcggca ggatcctttg ggggacagct gcttttccct gacagactgc caggaggtga cagcgaccta ccgacaggca ctgagggtct gctcaaagct Protein function: Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1. [The UniProt Consortium]