NCOA5 (Vector pENTR223.1, Accession No. BC056872)

Length: 948 Sequence: atggccggga tgcccgggac agcagagaca ttcgagaccc ccgagacttg cgggaccaca gacatgagag actcccgaga tcctatgtac aggagagaag gctcttatga ccgataccta cgaatggatg actattgcag gagaaaggat gactcttatt ttgaccgtta cagagatagc tttgatggac ggggccctcc aggcccagaa agtcagtctc gtgcaaaaga gcgtttgaaa cgtgaggaac ggcgtagaga agagctttat cgtcaatatt ttgaggaaat ccagagacgc tttgatgccg aaaggcccgt tgattgttct gtgattgtgg tcaacaaaca gacaaaagac tatgctgagt ctgtggggcg gaaggtgcga gacctgggca tggtagtgga cttgatcttc cttaacacag aagtgtcact gtcacaagcc ttggaggatg ttagcagggg aggttctcct tttgctattg tcatcaccca gcaacaccag attcaccgct cctgcacagt caacatcatg tttggaaccc cgcaagagca tcgcaacatg ccccaagcag atgccatggt gctggtggcc agaaattatg agcgttacaa gaatgagtgc cgggagaagg aacgtgagga gattgccaga caggcagcca agatggccga tgaagccatc ctgcaggaaa gagagagagg aggccctgag gagggagtgc gtgggggcca ccctccagcc atccagagcc tcatcaacct gctggcagac aacaggtacc tcactgctga agagactgac aagatcatca actacctgcg agagcggaag gagcggctga tgaggagcag caccgactct ctgcctggtg agctacgtgg cagggccgag gcccgatttc ccgccaacca ctcggggcga cctcgggtgc Protein function: Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2). [The UniProt Consortium]