MYO5B (Vector pUC, Accession No. BC033527)

Length: 1257 Sequence: ATGAAGAAAG CCCAGGACCT AGAAGCTGCC CAGGCATTGG CCCAGAGTGA GAGGAAGCGC CATGAGCTCA ACAGGCAGGT CACGGTCCAG CGGAAAGAGA AGGATTTCCA GGGCATGCTG GAGTACCACA AAGAGGACGA GGCCCTCCTC ATCCGGAACC TGGTGACAGA CTTGAAGCCC CAGATGCTGT CGGGCACAGT GCCCTGTCTC CCCGCCTACA TCCTCTACAT GTGCATCCGG CACGCGGACT ACACCAACGA CGATCTCAAG GTGCACTCCC TGCTGACCTC CACCATCAAC GGCATTAAGA AAGTCCTGAA AAAGCACAAT GATGACTTTG AGATGACGTC ATTCTGGTTA TCCAACACCT GCCGCCTTCT TCACTGTCTG AAGCAGTACA GCGGGGATGA GGGCTTCATG ACTCAGAACA CTGCAAAGCA GAATGAACAC TGTCTTAAGA ATTTTGACCT CACCGAATAC CGTCAGGTGC TGAGTGACCT TTCCATTCAG ATCTACCAGC AGCTCATTAA AATTGCCGAG GGCGTGTTAC AGCCGATGAT AGTTTCTGCC ATGTTGGAAA ATGAGAGCAT TCAGGGTCTA TCTGGTGTGA AGCCCACCGG CTACCGGAAG CGCTCCTCCA GCATGGCAGA TGGGGATAAC TCATACTGCC TGGAAGCTAT CATCCGCCAG ATGAATGCCT TTCATACAGT CATGTGTGAC CAGGGCTTGG ACCCTGAGAT CATCCTGCAG GTATTCAAAC AGCTCTTCTA CATGATCAAC GCAGTGACTC TTAACAACCT GCTCTTGCGG AAGGACGTCT GCTCTTGGAG CACAGGCATG CAACTCAGGT ACAATATAAG TCAGCTTGAG GAGTGGCTTC GGGGAAGAAA CCTTCACCAG AGTGGAGCAG TTCAGACCAT GGAACCTCTG ATCCAAGCAG CCCAGCTCCT GCAATTAAAG AAGAAAACCC AGGAGGACGC AGAGGCTATC TGCTCCCTGT GTACCTCCCT CAGCACCCAG CAGATTGTCA AAATTTTAAA CCTTTATACT CCCCTGAATG AATTTGAAGA ACGGGTAACA GTGGCCTTTA TACGAACAAT CCAGGCACAA CTACAAGAGC GGAATGACCC TCAGCAACTG CTATTAGATG CCAAGCACAT GTTTCCTGTT TTGTTTCCAT TTAATCCATC TTCTCTAACC ATGGACTCAA TCCACATCCC AGCGTGTCTC AATCTGGAAT TCCTCAATGA Protein function: May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis. [The UniProt Consortium]