MYO1G (Vector pUC, Accession No. BC117241)

Length: 3057 Sequence: atggaggacg aggaaggccc tgagtatggc aaacctgact ttgtgctttt ggaccaagtg accatggagg acttcatgag gaacctgcag ctcaggttcg agaagggccg catctacacc tacatcggtg aggtgctggt gtccgtgaac ccctaccagg agctgcccct gtatgggcct gaggccatcg ccaggtacca gggccgtgag ctctatgagc ggccacccca tctctatgct gtggccaacg ccgcctacaa ggcaatgaag caccggtcca gggacacctg catcgtcatc tcaggggaga gtggggcagg gaagacagaa gccagtaagc acatcatgca gtacatcgct gctgtcacca atccaagcca gagggctgag gtggagaggg tcaaggacgt gctgctcaag tccacctgtg tgctggaggc ctttggcaat gcccgcacca accgcaatca caactccagc cgctttggca agtacatgga catcaacttt gacttcaagg gggacccgat cggaggacac atccacagct acctactgga gaagtctcgg gtcctcaagc agcacgtggg tgaaagaaac ttccacgcct tctaccaatt gctgagaggc agtgaggaca agcagctgca tgaactgcac ttggagagaa accctgctgt atacaatttc acacaccagg gagcaggact caacatgact gtgcacagtg ccttggacag tgatgagcag agccaccagg cagtgaccga ggccatgagg gtcatcggct tcagtcctga agaggtggag tctgtgcatc gcatcctggc tgccatattg cacctgggaa acatcgagtt tgtggagacg gaggagggtg ggctgcagaa ggagggcctg gcagtggccg aggaggcact ggtggaccat gtggctgagc tgacggccac accccgggac ctcgtgctcc gctccctgct ggctcgcaca gttgcctcgg gaggcaggga actcatagag aagggccaca ctgcagctga ggccagctat gcccgggatg cctgtgccaa ggcagtgtac cagcggctgt ttgagtgggt ggtgaacagg atcaacagtg tcatggaacc ccggggccgg gatcctcggc gtgatggcaa ggacacagtc attggcgtgc tggacatcta tggcttcgag gtgtttcccg tcaacagttt cgagcagttc tgcatcaact actgcaatga gaagctgcag cagctattca tccagctcat cctgaagcag gaacaggaag agtacgagcg cgagggcatc acctggcaga gcgttgagta tttcaacaac gccaccattg tggatctggt ggagcggccc caccgtggca tcctggccgt gctggacgag gcctgcagct ctgctggcac catcactgac cgaatcttcc tgcagaccct ggacacgcac caccgccatc atctacacta caccagccgc cagctctgcc ccacagacaa gaccatggag tttggccgag acttccggat caagcactat gcaggggacg tcacgtactc cgtggaaggc ttcatcgaca agaacagaga tttcctcttc caggacttca agcggctgct gtacaacagc acggacccca ctctacgggc catgtggccg gacgggcagc aggacatcac agaggtgacc aagcgccccc tgacggctgg cacactcttc aagaactcca tggtggccct ggtggagaac cttgcctcca aggagccctt ctacgtccgc tgcatcaagc ccaatgagga caaggtagct gggaagctgg atgagaacca ctgtcgccac caggtcgcat acctggggct gctggagaat gtgagggtcc gcagggctgg cttcgcttcc cgccagccct actctcgatt cctgctcagg tacaagatga cctgtgaata cacatggccc aaccacctgc tgggctccga caaggcagcc gtgagcgctc tcctggagca gcacgggctg cagggggacg tggcctttgg ccacagcaag ctgttcatcc gctcaccccg gacactggtc acactggagc agagccgagc ccgcctcatc cccatcattg tgctgctatt gcagaaggca tggcggggca ccttggcgag gtggcgctgc cggaggctga gggctatcta caccatcatg cgctggttcc ggagacacaa ggtgcgggct cacctggctg agctgcagcg gcgattccag gctgcaaggc agccgccact ctacgggcgt gaccttgtgt ggccgctgcc ccctgctgtg ctgcagccct tccaggacac ctgccacgca ctcttctgca ggtggcgggc ccggcagctg gtgaagaaca tccccccttc agacatgccc cagatcaagg ccaaggtggc cgccatgggg gccctgcaag ggcttcgtca ggactggggc tgccgacggg cctgggcccg agactacctg tcctctgcca ctgacaatcc cacagcatca agcctgtttg ctcagcgact aaagacactt cgggacaaag atggcttcgg ggctgtgctc ttttcaagcc atgtccgcaa ggtgaaccgc ttccacaaga tccggaaccg ggccctcctg ctcacagacc agcacctcta caagctggac cctgaccggc agtaccgggt gatgcgggcc gtgccccttg aggcggtgac ggggctgagc gtgaccagcg gaggagacca gctggtggtg ctgcacgccc gcggccagga cgacctcgtg gtgtgcctgc accgctcccg gccgccattg gacaaccgcg ttggggagct ggtgggcgtg ctggccgcac actgccaggg ggagggccgc accctggagg ttcgcgtctc cgactgcatc ccactaagcc atcgcggggt ccggcgcctc atctccgtgg agcccaggcc ggagcagcca gagcccgatt tccgctgcgc tcgcggctcc ttcaccctgc tctggcccag Protein function: Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication. Also required in B-cells, where it regulates different membrane/cytoskeleton-dependent processes. Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis. [The UniProt Consortium]