MTMR9 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1650 Sequence: atggagtttg cggagctgat taagaccccg cgggtggaca atgtggtgct gcaccggcct ttctacccgg ctgtcgaggg caccctgtgc ctgacgggcc accacttgat cctgtcctcc cggcaggaca atacggagga gctgtggctc ctccattcaa acatcgacgc catcgacaag cgatttgtag gatcactggg taccatcatc ataaaatgta aagattttcg aattattcag ttggatattc ctggaatgga ggaatgcttg aatatagcca gttccattga ggcattgtct actctggact ccatcactct gatgtaccct ttcttttacc gtcctatgtt tgaagtgata gaagatggct ggcattcctt ccttcctgag caagaatttg aactctattc ttcagctacc agtgaatgga ggctaagcta tgtcaataag gaatttgctg tctgtccctc ttacccacca attgtcacag tgcccaaatc catcgatgat gaagctcttc ggaaggtagc tacatttcga catggagggc gcttcccagt actcagctat taccacaaaa aaaatgggat ggtaattatg cgaagtggtc agccactcac tggtacaaac gggaggaggt gcaaggagga cgagaagctg ataaatgcta ccctcagggc tggaaagcgt ggctacatca ttgacacccg atccctgaac gtggctcagc aaactagagc caaaggaggt ggctttgaac aagaagctca ttatcctcag tggaggcgaa ttcataagtc cattgagagg tatcacattc ttcaggagag cttaatcaaa cttgtggaag cttgtaatga ccaaacacat aacatggacc gatggctcag taaattggag gcctctaact ggctgactca catcaaagag attctgacaa ctgcctgcct agcggctcag tgcatcgaca gggaaggagc atcaatattg attcacggaa cagaaggaac tgattccaca ctccaggtga cctccttggc ccagatcatc ttagagccaa gaagcaggac cattcgtggt tttgaggccc tgattgaaag agagtggctg caggctggtc acccattcca gcagcgctgt gcactgtcag cctactgtaa caccaagcag aagtgggagg ctcctgtatt tcttctcttc ttggactgcg tgtggcagat ccttcgtcag tttccctgtt cttttgagtt taatgagaat ttcctcatca tgctctttga gcatgcttat gcctcacagt ttggaacatt tctgggcaac aatgaaagtg aaagatgtaa gttgaagcta cagcagaaga cgatgtcttt gtggtcctgg gttaatcagc ccagtgagct gagtaaattc accaatcccc tctttgaagc caacaacctt gtcatctggc cttcagttgc tccgcagagt cttccactgt gggaaggtat tttcctacgt tggaatagat cctctaagta tttggatgaa gcatatgaag aaatggttaa catcattgaa tataataaag aattacaagc aaaagtcaat atccttcgaa ggcagttggc agaactggaa acagaggacg ggatgcagga Protein function: Acts as an adapter for myotubularin-related phosphatases (PubMed:19038970, PubMed:22647598). Increases lipid phosphatase MTMR6 catalytic activity, specifically towards phosphatidylinositol 3,5- bisphosphate and MTMR6 binding affinity for phosphorylated phosphatidylinositols (PubMed:19038970, PubMed:22647598). Positively regulates lipid phosphatase MTMR7 catalytic activity. Increases MTMR8 catalytic activity towards phosphatidylinositol 3- phosphate (PubMed:22647598). The formation of the MTMR6-MTMR9 complex, stabilizes both MTMR6 and MTMR9 protein levels (PubMed:19038970). Stabilizes MTMR8 protein levels (PubMed:22647598). Plays a role in the late stages of macropinocytosis possibly by regulating MTMR6-mediated dephosphorylation of phosphatidylinositol 3-phosphate in membrane ruffles (PubMed:24591580). Negatively regulates autophagy, in part via its association with MTMR8 (PubMed:22647598). Negatively regulates DNA damage-induced apoptosis, in part via its association with MTMR6 (PubMed:19038970, PubMed:22647598). Does not bind mono-, di- and tri- phosphorylated phosphatidylinositols, phosphatidic acid and phosphatidylserine (PubMed:19038970). [The UniProt Consortium]