MRVI1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1794 Sequence: atggccctga acagccctca gcctggcccc gtggagagcg agctggggaa gcagctcttg aaaacgggct gggagggcag ccctctgccg agaagtccaa cccaggatgc ggcaggagtg ggtcccccag cctcccaggg gagaggccca gctggagagc cgatggggcc cgaggctggc tccaaagctg agcttccacc cactgtgtcc cggcccccgc tgctgcgagg gctctcctgg gacagtggcc ctgaagaacc tggcccccgg ctgcagaaag tgcttgccaa gctgccactg gcagaggaag aaaagcgttt tgcaggcaag gccggcggca agctggccaa ggcccctggt ctcaaagact ttcagataca agtgcagccc gtgcggatgc agaaactgac caagctccga gaggagcaca tcctgatgag aaatcagaac ttagtggggc tcaagcttcc agaccttagt gaagcagctg agcaggaaaa agggcttcct tctgaactct ccccagctat tgaggaagaa gagtcaaaga gtggcttaga tgtcatgcct aatatttctg atgtgctgct gcgcaaactg cgggtccaca ggagtctccc tggaagtgcc cctccactca ctgaaaagga agttgagaac gtgtttgtgc aactgtcctt ggcctttaga aatgacagct acactctgga atctagaatt aaccaggctg aaagggaacg caacctgaca gaggagaaca ctgagaaaga actggaaaac ttcaaagctt ccattacgtc ctcagcttca ctctggcacc actgtgagca ccgggaaacc taccagaagt tgctggagga catcgctgtc ctgcaccgcc tggctgcccg cctctccagc cgagctgagg tggtaggcgc cgtccgccag gaaaagcgca tgtcgaaagc aacggaagtg atgatgcagt atgtggagaa tctaaagagg acgtatgaga aggaccatgc ggagctcatg gagtttaaaa agcttgcaaa tcagaattca agccgcagct gtggcccctc tgaagatggg gtccctcgca cggcacggtc catgtccctc acgctgggaa agaatatgcc tcgccggagg gtcagcgttg ctgtggttcc taagtttaat gccctgaatc tgcctggcca aactcccagc tcatcatcca ttccctcctt accagccttg tcggaatcac ccaatgggaa aggcagccta cctgtcactt cagcactgcc tgcacttttg gaaaatggaa agacaaatgg ggacccagat tgtgaagcct ctgctcctgc gctgaccctg agctgcctgg aggagcttag tcaggagacc aaggccagga tggaggaaga agcctacagc aagggattcc aagaaggtct aaagaagacc aaagaacttc aagacctgaa ggaggaggag gaagaacaga agagtgagag tcctgaggaa cctgaagagg tagaagaaac tgaggaagag gaaaagggcc caagaagcag caaacttgaa gaattggtcc atttcttaca agtcatgtat cccaaactgt gtcagcactg gcaagtgatc tggatgatgg ctgcagtgat gctggtcttg actgttgtgc tggggctcta caattcctat aactcttgtg cagagcaggc tgatgggccc cttggaagat ccacttgctc ggcagcccag agggactcct ggtggagctc aggactccag catgagcagc ctacagagca Protein function: Plays a role as NO/PRKG1-dependent regulator of IP3-induced calcium release, its phosphorylation by PRKG1 inhibits bradykinin and IP3-induced calcium release from intracellular stores. Recruits PRKG1 to the endoplasmic reticulum and may mediate the assembly of PRKG1 and ITPR1 in a macrocomplex. Involved in PRKG1 signaling cascade leading to inhibition of platelet activation and aggregation. Mediates also NO- dependent inhibition of calcium signaling in gastrointestinal smooth muscle contributing to NO-dependent relaxation. [The UniProt Consortium]