MAP3K12 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 1704 Sequence: atggcttgcc tccatgagac ccgaacaccc tctccttcct ttgggggctt tgtgtctacc ctaagtgagg catccatgcg caagctggac ccagacactt ctgactgcac tcccgagaag gacctgacgc ctacccagtg tgtacttcga gatgtggtac cccttggtgg gcagggtggg ggagggccca gcccctcccc aggtggagag ccgccccctg agccttttgc caacagtgtc ctgcagctac atgagcagga tgcagggggc ccagggggag cagctgggtc acctgagagt cgggcatcca gagttcgagc tgacgaggtg cgactgcagt gccagagtgg cagtggcttc cttgagggcc tctttggctg cctgcgccct gtctggacca tgattggcaa agcctactcc actgagcaca agcagcagca ggaagacctt tgggaggtcc cctttgagga aatcctggac ctgcagtggg tgggctcagg ggcccagggt gctgtcttcc tggggcgctt ccacggggag gaggtggctg tgaagaaggt gcgagacctc aaagaaaccg acatcaagca cttgcgaaag ctgaagcacc ccaacatcat cactttcaag ggtgtgtgca cccaggctcc ctgctactgc atcctcatgg agttctgcgc ccagggccag ctgtatgagg tactgcgggc tggccgccct gtcaccccct ccttactggt tgactggtcc atgggcatcg ctggtggcat gaactacctg cacctgcaca agattatcca cagggatctc aagtcaccca acatgctaat cacctacgac gatgtggtga agatctcaga ttttggcact tccaaggagc tgagtgacaa gagcaccaag atgtcctttg cagggacagt agcctggatg gcccctgagg tgatccgcaa tgaacctgtg tctgagaagg tcgacatctg gtcctttggc gtggtgctat gggaactgct gactggtgag atcccctaca aagacgtaga ttcctcagcc attatctggg gtgtgggaag caacagtctc catctgcccg tgccctccag ttgcccagat ggtttcaaga tcctgcttcg ccagtgctgg aatagcaaac cacgaaatcg cccatcattc cgacagatcc tgctgcatct ggacattgcc tcagctgatg tactctccac accccaggag acttacttta agtcccaggc agagtggcgg gaagaagtaa aactgcactt tgaaaagatt aagtcagaag ggacctgtct gcaccgccta gaagaggaac tggtgatgag gaggagggag gagctcagac acgccctgga catcagggag cactatgaaa ggaagctgga gagagccaac aacctgtata tggaacttaa tgccctcatg ttgcagctgg aactcaagga gagggagctg ctcaggcgag agcaagcttt agagcggagg tgcccaggcc tgctgaagcc acacccttcc cggggccccc agcttccctc cctccatgaa agccactcgt attccttgta catagagaaa tatttatata aattatatat atatacatat atatatatat atgcgccaca taatcaacag aaagatgggg ctgtcccagc cgtaagtcag gctcgaggga gactgatccc Protein function: Part of a non-canonical MAPK signaling pathway (PubMed:28111074). Activated by APOE, enhances the AP-1-mediated transcription of APP, via a MAP kinase signal transduction pathway composed of MAP2K7 and MAPK1/ERK2 and MAPK3/ERK1 (PubMed:28111074). May be an activator of the JNK/SAPK pathway. [The UniProt Consortium]