MAGI3 (Vector pUC, Accession No. BC130409)

Length: 3378 Sequence: atgtcgaaga cgctgaagaa gaagaagcac tggctcagca aggtgcagga gtgcgccgtg tcctgggccg ggcccccggg cgacttcggc gcggagatcc gcggtggcgc ggagcgtggc gagttcccct acctggggcg gctccgcgag gagcccggcg ggggcacctg ctgcgtcgtc tcgggcaagg cgcccagccc aggcgatgtg ctgctggagg taaacgggac gcctgtcagc gggctcacca accgggacac cctggctgtc atccgccact tccgcgagcc catccgtctc aagactgtga aaccaggcaa agtcattaat aaagatttgc ggcattacct aagtcttcag tttcaaaaag gatcaattga ccacaaactg cagcaagtga tcagagataa tctctacttg agaaccattc catgcactac aagggccccc agggatggag aagtaccagg agtggattat aatttcattt ccgttgaaca gttcaaagca ctggaagaga gtggagcatt gttagaaagt gggacatatg atggaaactt ctatggaact cccaagcctc cagcagaacc cagccctttt cagccagatc cagttgatca agtcctcttt gataatgagt ttgatgcaga atctcaaaga aaacgaacga catctgtcag caagatggaa agaatggata gctctcttcc tgaagaggaa gaagatgagg acaaggaagc tattaatggc agtggaaacg cagaaaacag agagaggcat tctgagtcat ctgactggat gaagactgtt ccaagttaca accaaacaaa tagctccatg gactttagaa attatatgat gagagatgag actctggaac cactgcccaa aaactgggaa atggcctaca ctgacacagg gatgatctac ttcattgacc acaataccaa gacaaccacc tggttggatc ctcgtctttg taagaaagcc aaagcccctg aagactgtga agatggagag cttccttatg gctgggagaa aatagaggac cctcagtatg ggacatacta tgttgatcac cttaaccaga aaacccagtt tgaaaatcca gtggaggaag ccaaaaggaa aaagcagtta ggacaggttg aaattgggtc ttcaaaacca gatatggaaa aatcacactt cacaagagat ccatcccagc ttaaaggtgt ccttgttcga gcatcactga aaaaaagcac aatgggattt ggttttacta ttattggtgg agatagacct gatgagttcc tacaagtgaa aaatgtgctg aaagatggtc ccgcagctca ggatgggaaa attgcaccag gcgatgttat tgtagacatc aatggcaact gtgtcctcgg tcacactcat gcagatgttg tccagatgtt tcaattggta cctgtcaatc agtatgtaaa cctcacttta tgtcgtggtt atccacttcc tgatgacagt gaagatcctg ttgtggacat tgttgctgct acccctgtca tcaatggaca gtcattaacc aagggagaga cttgcatgaa tcctcaggat tttaagccag gagcaatggt tctggagcag aatggaaaat cgggacacac tttgactggt gatggtctca atggaccatc agatgcaagt gagcagagag tatccatggc atcgtcaggc agctcccagc ctgaactagt gactatccct ttgattaagg gccctaaagg gtttgggttt gcaattgctg acagccctac tggacagaag gtgaaaatga tactggatag tcagtggtgt caaggccttc agaaaggaga tataattaag gaaatatacc atcaaaatgt gcagaattta acacatctcc aagtggtaga ggtgctaaag cagtttccag taggtgctga tgtaccattg cttatcttaa gaggaggtcc tccttcacca accaaaactg ccaaaatgaa aacagataaa aaggaaaatg caggaagttt ggaggccata aatgagccta ttcctcagcc tatgcctttt ccaccgagca ttatcaggtc aggatcccca aaattggatc cttctgaggt ctacctgaaa tctaagactt tatatgaaga taaaccacca aacaccaaag atttggatgt ttttcttcga aaacaagagt cagggtttgg cttcagggtg ctaggaggag atggacctga ccagtctata tatattgggg ctattattcc cctgggagca gctgagaaag atggtcggct ccgcgcagct gatgaactaa tgtgcattga tggaattcct gttaaaggga aatcacacaa acaagtcttg gacctcatga caactgctgc tcgaaatggc catgtgttac taactgtcag acggaagatc ttctatggag aaaaacaacc cgaggacgac agctctcagg ccttcatttc aacacagaat ggatctcccc gcctgaaccg ggcagaggtc ccagccaggc ctgcacccca ggagccctat gatgttgtct tgcaacgaaa agaaaatgaa ggatttggct ttgtcatcct cacctccaaa aacaaaccac ctccaggagt tattcctcat aaaattggcc gagtcataga aggaagtccg gctgaccgct gtggaaaact gaaagttgga gatcatatct ctgcagtgaa tgggcagtcc attgttgaac tgtctcatga taacattgtt cagctgatca aagatgctgg tgtcaccgtc acactaacgg tcattgctga agaagagcat catggtccac catcaggaac aaactcagcc aggcaaagcc cagccctgca gcacaggccc atgggacagt cacaggccaa ccacatacct ggggacagaa gtgccctaga aggtgaaatt ggaaaagatg tctccacttc ttacagacat tcttggtcag accacaagca ccttgcacag cctgacaccg cagtaatttc agttgtaggc agtcggcaca atcagaacct tggttgttat ccagtagagc tggagagagg cccccggggc tttggattca gcctccgagg ggggaaggag tacaacatgg ggctgttcat ccttcgtctt gctgaagatg gtcctgccat caaagatggc agaattcatg ttggtgacca gattgttgaa atcaatgggg aacctacaca aggaatcaca catactcgag caattgagct cattcaggct ggtggaaata aagttcttct tcttttgagg ccaggaactg gcttgatacc tgaccatggt ttggctcctt ccggtctgtg ctcctacgtg aaacccgagc Protein function: Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2. [The UniProt Consortium]