LRCH1 (Vector pUC, Accession No. BC117472)

Length: 2292 Sequence: atggcgacgc cgggaagcga accccaacct ttcgtcccgg ccctttcggt agctactctg cacccacttc atcatcccca ccaccaccac caccaccatc agcaccacgg aggaaccggc gcccccggcg gggcgggtgg tggcggcggt ggcagcgggg gcttcaacct gcccttgaac cggggtctgg agcgcgcgct tgaggaggcg gccaactccg gggggctgaa cctgagcgcc aggaaattga aggaatttcc ccgtaccgca gcccccgggc atgacctctc ggacacggtg caggcagact tatctaaaaa cagactggtt gaagttccaa tggaattgtg ccattttgta tcactggaaa ttcttaatct gtatcacaac tgtatcagag tcattcctga ggccatcgtt aatctgcaga tgctgactta cctgaacttg agtcgaaatc agctgtccgc cctgcctgcc tgcctgtgtg gtctgcctct caaagtctta atcgcaagta acaacaaact tggatcatta ccagaagaga taggtcagct caaacagtta atggagctgg atgtcagctg caacgagatc acagcgttgc cccagcagat aggtcagttg aaatctctac gagaactgaa tgtcagaaga aattacctta aagttttacc acaagaacta gtagatcttc ccttggtaaa gtttgacttt tcctgcaaca aagtgctcgt gattccaatt tgttttagag agatgaagca gctgcaagtg ttactacttg agaataaccc tctgcagtct cctccagcac agatttgcac aaagggcaaa gttcacatat ttaagtatct gagcatacaa gcatgccaga ttaagacagc tgactccctt tatctccaca ccatggagag gccacattta caccagcacg tggaagatgg caagaaggat tctgattcgg gagttggaag tgataatgga gataagcgat tatctgccac cgagccttct gacgaagaca ctgttagcct caatgtgcca atgtcaaaca tcatggaaga agaacagatc atcaaggagg actcgtgcca tcgccttagc cccgttaaag gggaatttca tcaggaattt caaccggagc cttccctttt gggtgacagc accaactcag gagaagaaag agaccagttt actgatagag cagatggtct ccattcggaa tttatgaact ataaggcaag ggcagaagac tgtgaagagc tgttacggat agaagaggat gtgcactggc aaactgaggg cataataagt tcatccaaag atcaggacat ggatatagca atgatcgagc agctgagaga agcagtagat ttgctgcaag atcccaatgg attaagcaca gatattacag agagaagtgt tttaaaccta tatcctatgg gatcagcaga agccttagaa ttacaagatt ctgcactgaa tggtcaaata cagctggaga catctccggt gtgtgaggtg caaagtgatc taacattaca gagtaacggg agccagtatt ctccaaatga gattagagag aactcccctg cagtctctcc taccacaaac agcacagctc catttggcct gaagcctcga tcagacccag ccctcattct tcctcctatc tccttcaaca cacttacaca ggcacagaca tgggacagct ctagctacag tgttccatct gaaggagaca gtgacaatgt gtttctaaga cctcagagaa atttggaatc tatagacccg cagtttacaa tccggaggaa aatggagcag atgagagaag agaaagagct ggtggaacaa cttcgtgaga gcattgagat gagattgaag gtcagtctac acgaagacct gggggcagcc ctcatggatg gtgtcgtcct ctgccatctg gtcaaccaca tccgcccacg gtcggttgca agcatccatg tcccatcacc agcggttccc aaacttagca tggccaaatg cagaagaaat gtggaaaact ttttggaagc gtgccgaaaa ttaggagtac cagaggctga cctctgctct ccgtgtgaca tcctgcagtt ggattttcgt cacattcgaa agactgttga cactctgctg gcactcgggg agaaagcccc accaccaact tctgccctcc gctccaggga ccttataggc ttctgtcttg tccatattct ctttatagtg ctggtctata tcacttacca ctggaatgct ctgtccgcat Protein function: Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration. [The UniProt Consortium]