LPGAT1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1113 Sequence: atggctataa ctttggaaga agctccgtgg ctgggctggc tcttggtgaa agcactgatg aggtttgcct tcatggtcgt caacaacctg gttgctattc catcctacat ctgctatgta attatacttc agccccttcg agtgctggac agtaagcggt tctggtatat cgaaggaatc atgtataaat ggcttttagg aatggtagct tcctggggat ggtatgctgg atatacagtg atggaatggg gagaagatat taaagcagtt tcaaaagatg aagcagtgat gttggtgaat catcaggcaa caggagatgt gtgcacactg atgatgtgcc tccaggacaa aggactggtt gttgctcaga tgatgtggtt gatggatcat atttttaagt acacaaactt tggaattgtt tctctagttc atggagactt ctttataaga cagggaagat cttatcgtga ccaacagctg ctgcttctca agaagcactt agaaaataat tacaggagca gagatcgaaa atggattgtt ttgtttccag aagggggctt cctcaggaag aggcgagaaa caagtcaggc atttgccaag aaaaataact tgccatttct tacaaatgtt actctgccaa ggtctggggc aacaaaaatt attttgaatg cacttgtagc acaacagaaa aatggaagtc cagcaggagg agatgctaaa gaattagaca gcaaatcaaa aggcctccag tggataatag atacaacgat agcttatccc aaagctgaac ctatagatat tcaaacctgg atccttggat acaggaaacc aacagtcaca catgtacatt acaggatctt tccaattaaa gatgtacccc tggagactga tgaccttacc acttggctct atcagcggtt tgttgaaaaa gaagacctct tatcacattt ttatgaaaca ggagcttttc caccttccaa gggccataag gaagctgttt ccagggagat gaccctcagc aacttgtgga tatttctcat acagtctttt gcatttttgt caggctatat gtggtacaac atcattcagt atttttacca ttgcctgttt Protein function: Catalyzes the transfert of an acyl group from an acyl-CoA to a lysophosphatidylglycerol (LPG) leading to biosynthesis of phosphatidylglycerol, a precursor for cardiolipin synthesis (PubMed:15485873). Uses various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl- CoAs and oleoyl-CoA as acyl donors (PubMed:15485873). Prefers oleoyl- LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl- CoA as an acyl donor (PubMed:15485873). In vitro can also catalyzes the transfert of an acyl group from an acyl-CoA to a monoacylglycerol leading to diacylglycerol synthesis, a precursor of triacylglycerol and plays a role in hepatic triacylglycerol synthesis and secretion. Prefers the sn-2-monoacylglycerol to rac-1- monoacylglycerol as acyl acceptor. [The UniProt Consortium]