LPCAT2 (Vector pUC, Accession No. BC002472)

Length: 1635 Sequence: atgagccggt gcgcccaggc ggcggaagtg gcggccacag tgccaggtgc cggcgtcggg aacgtggggc tgcggccgcc catggtgccc cgtcaggcgt ccttcttccc gccgccggtg ccgaacccct tcgtgcagca gacgcagatc ggctccgcga ggcgggtcca gattgtcctt cttgggatta tcttgcttcc aattcgtgtc ttattggttg cgttaatttt attacttgca tggccatttg ctgcaatttc aacagtatgc tgtcctgaaa agctgaccca cccaataact ggttggagga ggaaaattac tcaaacagct ttgaaatttc tgggtcgtgc tatgttcttt tcaatgggat ttatagttgc tgtaaaagga aagattgcaa gtcctttgga agcaccagtt tttgttgctg cccctcattc aacattcttt gatggaattg cctgtgttgt agctgggtta ccttctatgg tatctcgaaa tgagaatgca caagtccctc tgattggcag actgttacgg gctgtgcaac cagttttggt gtcccgtgta gatccggatt cccgaaaaaa cacaataaat gaaataataa agcgaacaac atcaggagga gaatggcccc agatactagt tttcccagaa ggtacttgta ctaatcgttc ctgtttgatt acttttaaac caggagcctt cattccagga gttccagtgc agccagtcct cctcagatac ccaaacaagc tggatactgt gacctggaca tggcaaggat atacattcat tcagctttgt atgcttactt tctgccagct cttcacaaag gtagaagttg agtttatgcc agttcaagta ccaaatgatg aagaaaaaaa tgatcctgtc ctttttgcca ataaagtccg gaatttaatg gcagaagctc tgggaatacc agtaacagat catacctatg aagactgcag attgatgatt tcagcaggac agctaacatt gcctatggaa gctgggctgg tggaatttac taaaattagc cgaaaattga aattagattg ggatggtgtt cgtaagcatt tggatgaata tgcatctatt gcgagttcct caaaaggagg aagaattgga attgaagaat tcgccaagta tttaaagttg cctgtttcag atgtcttgag acaacttttt gcactctttg acaggaacca tgatggcagc attgacttcc gagagtatgt gattggcctg gctgtcttgt gcaacccttc caacacagag gagatcatcc aggtggcatt taagctgttt gacgttgatg aggatggcta cataacggag gaagagttct ccaccattct acaggcttcc cttggagtgc ctgaccttga tgtttctggt ctcttcaagg aaatagccca aggggactca atttcctatg aggaatttaa aagttttgcc ttaaagcatc cagaatatgc taagatattt acaacatacc tagacctcca gacgtgccat gtgttttcat taccaaaaga agtccagaca accccctcca ccgccagtaa taaagtcagc cctgaaaagc atgaagagag tacctcagac aaaaaagatg Protein function: Exhibits both acyltransferase and acetyltransferase activities (PubMed:17182612, PubMed:20363836, PubMed:21498505). Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero- 3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn- glycero-3-phosphocholine or PC) (PubMed:21498505). Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:20363836). Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2- acetyl-sn-glycero-3-phosphocholine (PAF) (PubMed:17182612). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Involved in the regulation of lipid droplet number and size (PubMed:25491198). [The UniProt Consortium]