LANCL1 (Vector pENTR223.1, Accession No. BC028685)

Length: 1200 Sequence: atggctcaaa gggccttccc gaatccttat gctgattata acaaatccct ggccgaaggc tactttgatg ctgccgggag gctgactcct gagttctcac aacgcttgac caataagatt cgggagcttc ttcagcaaat ggagagaggc ctgaaatcag cagaccctcg ggatggcacc ggttacactg gctgggcagg tattgctgtg ctttacttac atctttatga tgtatttggg gaccctgcct acctacagtt agcacatggc tatgtaaagc aaagtctgaa ctgcttaacc aagcgctcca tcaccttcct ttgtggggat gcaggccccc tggcagtggc cgctgtgcta tatcacaaga tgaacaatga gaagcaggca gaagattgca tcacacggct aattcaccta aataagattg atcctcatgc tccaaatgaa atgctctatg ggcgaatagg ctacatctat gctcttcttt ttgtcaataa gaactttgga gtggaaaaga ttcctcaaag ccatattcag cagatttgtg aaacaatttt aacctctgga gaaaacctag ctaggaagag aaacttcacg gcaaagtctc cactgatgta tgaatggtac caggaatatt atgtaggggc tgctcatggc ctggctggaa tttattacta cctgatgcag cccagccttc aagtgagcca agggaagtta catagtttgg tcaagcccag tgtagactac gtctgccagc tgaaattccc ttctggcaat taccctccat gtataggtga taatcgagat ctgcttgtcc attggtgcca tggcgcccct ggggtaatct acatgctcat ccaggcctat aaggtattca gagaggaaaa gtatctctgt gatgcctatc agtgtgctga tgtgatctgg caatatgggt tgctgaagaa gggatatggg ctgtgccacg gttctgcagg gaatgcctat gccttcctga cactctacaa cctcacacag gacatgaagt acctgtatag ggcctgtaag tttgctgaat ggtgcttaga gtatggagaa catggatgca gaacaccaga cacccctttc tctctctttg aaggaatggc tggaacaata tatttcctgg ctgacctgct agtccccaca aaagccaggt tccctgcatt Protein function: Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4- dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione (PubMed:19528316). [The UniProt Consortium]