KIAA0748 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pU

Length: 1152 Sequence: atgactgggg ggaccaacaa gactagttca agcatctcag aaattctgga caaagtgcaa gaagatgcag aagatgtcct cttcagtctg ggctttggcc aagaggatca caaagacact tctcggatac ccgcccgatt tttcaccacc ccctctcagg ccaagggcat tgatttccag ctcttcctga agtcccaggt gcggaggatt gaaatggaag acccctgcct catgctggcc agcaggttta agcaggtgca aacactggct gtcactgctg atgccttctt ctgtctctac tcctatgtgt ctaagacacc tgtccaaaag ttcacaccat cccacatgtt ctggaattgc aaccatccaa ctgatgtgcc atccatcagg attctgtccc gagagcctga accccagtca cccagagacc gccttcggaa agccatctcc aagatgtgtc tgtacacatg cccccgagac cggccaccac caccccacaa cacccccaaa aggaacagtt tggaccaagt tgtgttggaa gtgatggaca aagtgaaaga agagaagcag ttcctccagc aagactctga tttggggcaa ttctcacagg aagatcctgt gccccctgct gagggtaaga agttgcccac ttctccctat ccatgtgtct tctgctgtga agaggaaaca cagcagagga tgtccacagt gctagcacca tcccaaactc tggattcgaa ccccaaggta ccctgttgca cacattctct gcccatagaa gatccacagt ggagcacaga cccagctcag ataaggagag agctgtgtag tctaccagcc accaatacgg aaacccatcc agccaaggat gagactttct ggaaaagaaa gagcagagca agaaagagcc tcttccagaa gaatctcatg ggcaggaagg ttaagtcctt ggacctgtcc atcacccagc agaaatggaa gcagagtgta gacagaccag aactgcgtcg gtctttaagc cagcagccac aggacacttt tgacttggag gaggtgcaaa gcaacagtga ggaggagcag agtcagagtc gctggcccag cagacccagg cacccccacc accaccagac ttttgctggc aaagactcgt Protein function: Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment. [The UniProt Consortium]