KCNE1 (Vector pENTR223.1, Accession No. BC036452)

Length: 318 Sequence: atgatcctgt ctaacaccac agcggtgacg ccctttctga ccaagctgtg gcaggagaca gttcagcagg gtggcaacat gtcgggcctg gcccacaggt ccccccgcag cggtgacggc aagctggagg ccctctacgt cctcatggta ctgggattct tcggcttctt caccctgggc atcatgctga gctacatccg ctccaagaag ctggagcact cgaacgaccc attcaacgtc tacatcgagt ccgatgcctg gcaagagaag gacaaggcct atgtccaggc ccgggtcctg gagagctaca Protein function: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:19219384). Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr). [The UniProt Consortium]